Details for: EIF2B3

Gene ID: 8891

Symbol: EIF2B3

Ensembl ID: ENSG00000070785

Description: eukaryotic translation initiation factor 2B subunit gamma

Associated with

Other Information

Genular Protein ID: 3504908248

Symbol: EI2BG_HUMAN

Name: Translation initiation factor eIF2B subunit gamma

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10900014

Title: Identification of eIF2B gamma and eIF2 gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach.

PubMed ID: 10900014

DOI: 10.1073/pnas.97.15.8566

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25858979

Title: Stress responses. Mutations in a translation initiation factor identify the target of a memory-enhancing compound.

PubMed ID: 25858979

DOI: 10.1126/science.aaa6986

PubMed ID: 27023709

Title: Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B.

PubMed ID: 27023709

DOI: 10.1007/s10969-016-9203-3

PubMed ID: 31048492

Title: Structural basis for eIF2B inhibition in integrated stress response.

PubMed ID: 31048492

DOI: 10.1126/science.aaw4104

PubMed ID: 11835386

Title: Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.

PubMed ID: 11835386

DOI: 10.1002/ana.10112

PubMed ID: 19158808

Title: Identification of novel EIF2B mutations in Chinese patients with vanishing white matter disease.

PubMed ID: 19158808

DOI: 10.1038/jhg.2008.10

PubMed ID: 21484434

Title: Adult-onset leukoencephalopathies with vanishing white matter with novel missense mutations in EIF2B2, EIF2B3, and EIF2B5.

PubMed ID: 21484434

DOI: 10.1007/s10048-011-0284-7

Sequence Information:

  • Length: 452
  • Mass: 50240
  • Checksum: 6F73137F59E52773
  • Sequence:
  • MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 
    KALCAEFKMK MKPDIVCIPD DADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 
    FRAYDASLAM LMRKGQDSIE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 
    VIKGSILQKH PRIRFHTGLV DAHLYCLKKY IVDFLMENGS ITSIRSELIP YLVRKQFSSA 
    SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLNLAPYDA CWNACRGDRW EDLSRSQVRC 
    YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SALCPEEPPV HSSAQIVSKH LVGVDSLIGP 
    ETQIGEKSSI KRSVIGSSCL IKDRVTITNC LLMNSVTVEE GSNIQGSVIC NNAVIEKGAD 
    IKDCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI

Genular Protein ID: 3258226662

Symbol: Q9HA31_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 283
  • Mass: 31511
  • Checksum: 64906C44D0CB982B
  • Sequence:
  • MANEADLDEE LVIKGSILQK HPRIRFHTGL VDAHLYCLKK YIVDFLMENG SITSIRSELI 
    PYLVRKQFSS ASSQQGQEEK EEDLKKKELK SLDIYSFIKE ANTLNLAPYD ACWNACRGDR 
    WEDLSRSQVR CYVHIMKEGL CSRVSTLGLY MEANRQVPKL LSALCPEEPP VHSSAQIVSK 
    HLVGVDSLIG PETQIGEKSS IKRSVIGSSC LIKDRVTITN CLLMNSVTVE EGSNIQGSVI 
    CNNAVIEKGA DIKDCLIGSG QRIEAKAKRV NEVIVGNDQL MEI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.