Details for: PID1
Gene ID: 55022
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: PID1
Ensembl ID: ENSG00000153823
Description: phosphotyrosine interaction domain containing 1
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 41.73rCSI 67.12%PRS 72.83
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CSI 41.03rCSI 68.86%PRS 71.6
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CSI 37.99rCSI 69.03%PRS 79.5
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CSI 34.72rCSI 61.31%PRS 71.07
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CSI 32.53rCSI 58.22%PRS 86.03
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CSI 27.5rCSI 60.51%PRS 69.69
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CSI 24.88rCSI 59.82%PRS 88.43
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CSI 21.93rCSI 38.45%PRS 82.2
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CSI 18.91rCSI 45.95%PRS 69.37
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CSI 16.58rCSI 59.65%PRS 69.56
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CSI 15.58rCSI 58.88%PRS 71.88
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CSI 14.56rCSI 33.23%PRS 79.52
-
CSI 14.26rCSI 37.16%PRS 88.1
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CSI 14.04rCSI 67.24%PRS 87.31
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CSI 13.49rCSI 16.11%PRS 71.76
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CSI 12.48rCSI 16.03%PRS 77.77
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CSI 12.3rCSI 9.48%PRS 89.93
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CSI 11.64rCSI 33.72%PRS 77.5
-
CSI 11.47rCSI 9.89%PRS 86.47
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CSI 11.08rCSI 11.61%PRS 84.38
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CSI 11.06rCSI 25.29%PRS 87.79
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CSI 11.02rCSI 13.72%PRS 93.35
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CSI 10.66rCSI 25.46%PRS 89.62
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CSI 10.41rCSI 27.71%PRS 74.33
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CSI 10.12rCSI 12.58%PRS 69.45
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CSI 10.09rCSI 31.53%PRS 72.93
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CSI 9.89rCSI 14.18%PRS 78
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CSI 9.69rCSI 19.46%PRS 79.31
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CSI 9.61rCSI 8.82%PRS 92.36
-
CSI 9.54rCSI 17.14%PRS 81.21
-
CSI 9.36rCSI 49.75%PRS 78.74
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CSI 9.23rCSI 15.97%PRS 80.2
-
CSI 9.08rCSI 29.53%PRS 84.02
-
CSI 9.07rCSI 14.85%PRS 78.31
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CSI 9.06rCSI 51.2%PRS 74.57
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CSI 9.01rCSI 53.07%PRS 72.01
-
CSI 8.92rCSI 33.65%PRS 70.5
-
CSI 8.63rCSI 13.77%PRS 78.86
-
CSI 8.62rCSI 24.79%PRS 78.73
-
CSI 8.17rCSI 17.98%PRS 89.63
-
CSI 7.92rCSI 30.8%PRS 84.79
-
CSI 7.88rCSI 13.89%PRS 90.23
-
CSI 7.78rCSI 8.98%PRS 79.32
-
CSI 7.74rCSI 39.62%PRS 89.25
-
CSI 7.61rCSI 23.79%PRS 75.09
-
CSI 7.54rCSI 17.4%PRS 76.44
-
CSI 7.47rCSI 18.98%PRS 80.94
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CSI 7.46rCSI 27.95%PRS 80.99
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CSI 7.14rCSI 9.16%PRS 83.22
-
CSI 7.12rCSI 5.94%PRS 83.37
-
CSI 6.92rCSI 10.44%PRS 91.27
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CSI 6.91rCSI 7.22%PRS 84.43
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CSI 6.86rCSI 15.31%PRS 92.09
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CSI 6.6rCSI 14.81%PRS 94.96
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CSI 6.49rCSI 8.37%PRS 72.76
-
CSI 6.47rCSI 36.06%PRS 88.27
-
CSI 6.25rCSI 9.05%PRS 95.57
-
CSI 6.16rCSI 21.09%PRS 73.42
-
CSI 6.12rCSI 7.61%PRS 87.02
-
CSI 5.88rCSI 7.87%PRS 84.36
-
CSI 5.75rCSI 6.95%PRS 92.55
-
CSI 5.75rCSI 6.75%PRS 87.71
-
CSI 5.64rCSI 14.72%PRS 83.8
-
CSI 5.25rCSI 13.85%PRS 91.66
-
CSI 5.24rCSI 5.74%PRS 88.4
-
CSI 5.17rCSI 12.8%PRS 87.17
-
CSI 5.14rCSI 11.35%PRS 74.63
-
CSI 4.94rCSI 4.01%PRS 86.33
-
CSI 4.88rCSI 19.89%PRS 78.97
-
CSI 4.84rCSI 9.06%PRS 77.1
-
CSI 4.82rCSI 4.48%PRS 87.88
-
CSI 4.74rCSI 7.54%PRS 81.33
-
CSI 4.72rCSI 13.93%PRS 85.93
-
CSI 4.71rCSI 6.17%PRS 94.26
-
CSI 4.57rCSI 6.33%PRS 83.38
-
CSI 4.5rCSI 10.56%PRS 85.34
-
CSI 4.38rCSI 8.26%PRS 92.68
-
CSI 4.16rCSI 11.47%PRS 83.11
-
CSI 4.13rCSI 3.81%PRS 87.9
-
CSI 4.12rCSI 8.47%PRS 74.23
-
CSI 4.1rCSI 15.61%PRS 79.23
-
CSI 4.05rCSI 5.09%PRS 93.32
-
CSI 4.04rCSI 9.67%PRS 75.03
-
CSI 3.96rCSI 12.68%PRS 85.01
-
CSI 3.96rCSI 6.04%PRS 86.55
-
CSI 3.87rCSI 7.68%PRS 82.93
-
CSI 3.7rCSI 8.3%PRS 72.34
-
CSI 3.43rCSI 8.95%PRS 80.84
-
CSI 3.38rCSI 3.5%PRS 89.24
-
CSI 3.34rCSI 10.99%PRS 73.88
-
CSI 3.27rCSI 9.2%PRS 82.25
-
CSI 3.21rCSI 4.98%PRS 88.69
-
CSI 3.13rCSI 14.67%PRS 94.48
-
CSI 3.07rCSI 4.71%PRS 93.13
-
CSI 3rCSI 42.61%PRS 78.6
-
CSI 2.99rCSI 4.72%PRS 87.79
-
CSI 2.96rCSI 9.92%PRS 71.94
-
CSI 2.94rCSI 3.78%PRS 88.99
-
CSI 2.88rCSI 16.98%PRS 78.06
-
CSI 2.84rCSI 29.43%PRS 80.96
-
CSI 0.3rCSI 2.7%PRS 89.8%
-
CSI 0.6rCSI 3.3%PRS 89.1%
-
CSI 0.6rCSI 3.1%PRS 89.8%
-
CSI 0.7rCSI 3.1%PRS 89.7%
-
CSI 0.8rCSI 5.0%PRS 79.7%
-
CSI 0.8rCSI 5.0%PRS 93.8%
-
CSI 0.8rCSI 2.3%PRS 91.0%
-
CSI 0.9rCSI 9.6%PRS 82.9%
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CSI 1.2rCSI 5.8%PRS 81.1%
-
CSI 1.2rCSI 10.3%PRS 76.9%
-
CSI 1.2rCSI 3.5%PRS 90.0%
-
CSI 1.3rCSI 10.9%PRS 82.8%
-
CSI 1.4rCSI 21.2%PRS 87.7%
-
CSI 1.4rCSI 3.6%PRS 91.0%
-
CSI 1.4rCSI 2.1%PRS 91.6%
-
CSI 1.4rCSI 8.9%PRS 81.6%
-
CSI 1.4rCSI 1.7%PRS 85.2%
-
CSI 1.4rCSI 4.4%PRS 89.6%
-
CSI 1.6rCSI 32.4%PRS 77.1%
-
CSI 1.8rCSI 4.7%PRS 89.8%
-
CSI 1.8rCSI 5.8%PRS 83.5%
-
CSI 1.8rCSI 8.5%PRS 94.9%
-
CSI 1.8rCSI 13.5%PRS 76.3%
-
CSI 1.9rCSI 8.3%PRS 75.5%
-
CSI 2.1rCSI 8.5%PRS 91.3%
-
CSI 2.1rCSI 9.2%PRS 91.6%
-
CSI 2.1rCSI 43.6%PRS 78.0%
-
CSI 2.1rCSI 2.7%PRS 90.9%
-
CSI 2.3rCSI 10.1%PRS 71.6%
-
CSI 2.3rCSI 4.9%PRS 75.1%
-
CSI 2.3rCSI 5.6%PRS 88.4%
-
CSI 2.4rCSI 58.4%PRS 69.2%
-
CSI 2.5rCSI 17.7%PRS 77.1%
-
CSI 2.6rCSI 61.9%PRS 69.6%
-
CSI 2.6rCSI 15.9%PRS 88.9%
-
CSI 2.8rCSI 9.0%PRS 86.9%
-
CSI 2.8rCSI 29.4%PRS 81.0%
-
CSI 2.9rCSI 17.0%PRS 78.1%
-
CSI 2.9rCSI 3.8%PRS 89.0%
-
CSI 3.0rCSI 9.9%PRS 71.9%
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CSI 3.0rCSI 4.7%PRS 87.8%
-
CSI 3.0rCSI 42.6%PRS 78.6%
-
CSI 3.1rCSI 4.7%PRS 93.1%
-
CSI 3.1rCSI 14.7%PRS 94.5%
-
CSI 3.2rCSI 5.0%PRS 88.7%
-
CSI 3.3rCSI 9.2%PRS 82.3%
-
CSI 3.3rCSI 11.0%PRS 73.9%
-
CSI 3.4rCSI 3.5%PRS 89.2%
-
CSI 3.4rCSI 9.0%PRS 80.8%
-
CSI 3.7rCSI 8.3%PRS 72.3%
-
CSI 3.9rCSI 7.7%PRS 82.9%
-
CSI 4.0rCSI 6.0%PRS 86.6%
-
CSI 4.0rCSI 12.7%PRS 85.0%
-
CSI 4.0rCSI 9.7%PRS 75.0%
-
CSI 4.1rCSI 5.1%PRS 93.3%
-
CSI 4.1rCSI 15.6%PRS 79.2%
-
CSI 4.1rCSI 8.5%PRS 74.2%
-
CSI 4.1rCSI 3.8%PRS 87.9%
-
CSI 4.2rCSI 11.5%PRS 83.1%
-
CSI 4.4rCSI 8.3%PRS 92.7%
-
CSI 4.5rCSI 10.6%PRS 85.3%
-
CSI 4.6rCSI 6.3%PRS 83.4%
-
CSI 4.7rCSI 6.2%PRS 94.3%
-
CSI 4.7rCSI 13.9%PRS 85.9%
-
CSI 4.7rCSI 7.5%PRS 81.3%
-
CSI 4.8rCSI 4.5%PRS 87.9%
-
CSI 4.8rCSI 9.1%PRS 77.1%
-
CSI 4.9rCSI 19.9%PRS 79.0%
-
CSI 4.9rCSI 4.0%PRS 86.3%
-
CSI 5.1rCSI 11.4%PRS 74.6%
-
CSI 5.2rCSI 12.8%PRS 87.2%
-
CSI 5.2rCSI 5.7%PRS 88.4%
-
CSI 5.3rCSI 13.9%PRS 91.7%
-
CSI 5.6rCSI 14.7%PRS 83.8%
-
CSI 5.8rCSI 6.8%PRS 87.7%
-
CSI 5.8rCSI 7.0%PRS 92.6%
-
CSI 5.9rCSI 7.9%PRS 84.4%
-
CSI 6.1rCSI 7.6%PRS 87.0%
-
CSI 6.2rCSI 21.1%PRS 73.4%
-
CSI 6.3rCSI 9.1%PRS 95.6%
-
CSI 6.5rCSI 36.1%PRS 88.3%
-
CSI 6.5rCSI 8.4%PRS 72.8%
-
CSI 6.6rCSI 14.8%PRS 95.0%
-
CSI 6.9rCSI 15.3%PRS 92.1%
-
CSI 6.9rCSI 7.2%PRS 84.4%
-
CSI 6.9rCSI 10.4%PRS 91.3%
-
CSI 7.1rCSI 5.9%PRS 83.4%
-
CSI 7.1rCSI 9.2%PRS 83.2%
-
CSI 7.5rCSI 28.0%PRS 81.0%
-
CSI 7.5rCSI 19.0%PRS 80.9%
-
CSI 7.5rCSI 17.4%PRS 76.4%
-
CSI 7.6rCSI 23.8%PRS 75.1%
-
CSI 7.7rCSI 39.6%PRS 89.3%
-
CSI 7.8rCSI 9.0%PRS 79.3%
-
CSI 7.9rCSI 13.9%PRS 90.2%
-
CSI 7.9rCSI 30.8%PRS 84.8%
-
CSI 8.2rCSI 18.0%PRS 89.6%
-
CSI 8.6rCSI 24.8%PRS 78.7%
-
CSI 8.6rCSI 13.8%PRS 78.9%
-
CSI 8.9rCSI 33.7%PRS 70.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 3521268886
Symbol: PCLI1_HUMAN
Name: PTB-containing, cubilin and LRP1-interacting protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15221005
Title: Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.
PubMed ID: 15221005
PubMed ID: 16815647
Title: Identification and characterization of NYGGF4, a novel gene containing a phosphotyrosine-binding (PTB) domain that stimulates 3T3-L1 preadipocytes proliferation.
PubMed ID: 16815647
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17124247
Title: Identification of the ligands of protein interaction domains through a functional approach.
PubMed ID: 17124247
Sequence Information:
- Length: 250
- Mass: 28272
- Checksum: 3C2F4AE5254D2885
- Sequence:
MFSLPLSLPL CEDTAFLPSK CCSSHKTIKQ ARTLIMIFLA SGTHFQTMLK SKLNVLTLKK EPLPAVIFHE PEAIELCTTT PLMKTRTHSG CKVTYLGKVS TTGMQFLSGC TEKPVIELWK KHTLAREDVF PANALLEIRP FQVWLHHLDH KGEATVHMDT FQVARIAYCT ADHNVSPNIF AWVYREINDD LSYQMDCHAV ECESKLEAKK LAHAMMEAFR KTFHSMKSDG RIHSNSSSEE VSQELESDDG