Details for: PPP2R3A
Gene ID: 5523
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: PPP2R3A
Ensembl ID: ENSG00000073711
Description: protein phosphatase 2 regulatory subunit B''alpha
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 34.37rCSI 49.31%PRS 45.24
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CSI 25.07rCSI 35.54%PRS 51.34
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CSI 19.95rCSI 50.6%PRS 44.74
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CSI 16.39rCSI 34.85%PRS 56.17
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CSI 12.48rCSI 14.43%PRS 44.92
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CSI 11.7rCSI 15.64%PRS 64.16
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CSI 10.57rCSI 14.64%PRS 57.56
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CSI 9.99rCSI 15.94%PRS 48
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CSI 9.51rCSI 21%PRS 41.86
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CSI 8.01rCSI 16.09%PRS 44.24
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CSI 7.53rCSI 9.66%PRS 52.55
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CSI 7.52rCSI 8.68%PRS 48.67
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CSI 7.49rCSI 6.27%PRS 59.81
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CSI 7.43rCSI 10.33%PRS 54.01
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CSI 7.32rCSI 9.97%PRS 47.41
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CSI 7.18rCSI 16.4%PRS 47.31
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CSI 6.89rCSI 16.41%PRS 56.25
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CSI 6.53rCSI 16.96%PRS 58.93
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CSI 6.53rCSI 4.83%PRS 47.77
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CSI 6.38rCSI 8.19%PRS 48.48
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CSI 6.23rCSI 20.07%PRS 53.64
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CSI 6.07rCSI 35.01%PRS 54.86
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CSI 5.9rCSI 9.72%PRS 60.31
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CSI 5.77rCSI 13.31%PRS 44.83
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CSI 5.76rCSI 7.43%PRS 38.72
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CSI 5.54rCSI 14.8%PRS 46.54
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CSI 5.51rCSI 8.1%PRS 49.14
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CSI 5.26rCSI 9.56%PRS 47.46
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CSI 5.23rCSI 6.25%PRS 37.42
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CSI 5.14rCSI 12.55%PRS 49.08
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CSI 5.11rCSI 8.96%PRS 47.24
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CSI 5.09rCSI 17.42%PRS 44.6
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CSI 4.75rCSI 24.32%PRS 59.22
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CSI 4.71rCSI 16.94%PRS 36.25
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CSI 4.67rCSI 4.5%PRS 45.5
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CSI 4.56rCSI 18.42%PRS 53.6
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CSI 4.26rCSI 11.01%PRS 50.2
-
CSI 4.24rCSI 16.02%PRS 38.43
-
CSI 4.23rCSI 7.93%PRS 43.79
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CSI 4.18rCSI 5.2%PRS 35.85
-
CSI 4.17rCSI 6.63%PRS 47.47
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CSI 4.12rCSI 16.1%PRS 31.45
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CSI 4.02rCSI 3.18%PRS 42.08
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CSI 3.82rCSI 11.95%PRS 39.05
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CSI 3.82rCSI 6.25%PRS 44.77
-
CSI 3.8rCSI 7.71%PRS 35.45
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CSI 3.79rCSI 9.89%PRS 54.33
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CSI 3.77rCSI 23.55%PRS 46.97
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CSI 3.75rCSI 9.11%PRS 36.36
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CSI 3.73rCSI 7.75%PRS 52.32
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CSI 3.67rCSI 6.48%PRS 36.63
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CSI 3.45rCSI 12.91%PRS 47.3
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CSI 3.4rCSI 3.27%PRS 55.4
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CSI 3.33rCSI 3.57%PRS 53.74
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CSI 3.31rCSI 4.42%PRS 55.91
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CSI 3.24rCSI 2.68%PRS 53.93
-
CSI 3.22rCSI 6.4%PRS 53.11
-
CSI 3.21rCSI 15.38%PRS 54.19
-
CSI 3.17rCSI 18.67%PRS 39.03
-
CSI 3.16rCSI 9.33%PRS 58.5
-
CSI 3.16rCSI 23.2%PRS 42.11
-
CSI 3.13rCSI 4.28%PRS 49.37
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CSI 3.11rCSI 3.26%PRS 51.82
-
CSI 3.07rCSI 6.65%PRS 43.69
-
CSI 3.04rCSI 3.65%PRS 53.29
-
CSI 2.96rCSI 2.75%PRS 54.96
-
CSI 2.93rCSI 2.27%PRS 56.3
-
CSI 2.87rCSI 40.74%PRS 46.63
-
CSI 2.84rCSI 14.32%PRS 57.3
-
CSI 2.8rCSI 29.63%PRS 54.08
-
CSI 2.72rCSI 3.98%PRS 58.91
-
CSI 2.72rCSI 4.37%PRS 39.73
-
CSI 2.68rCSI 7.95%PRS 65.45
-
CSI 2.66rCSI 23.01%PRS 53.07
-
CSI 2.5rCSI 11.96%PRS 54.51
-
CSI 2.5rCSI 4.19%PRS 37.58
-
CSI 2.48rCSI 4.44%PRS 53.86
-
CSI 2.47rCSI 6.43%PRS 53.08
-
CSI 2.46rCSI 4.25%PRS 45.17
-
CSI 2.42rCSI 3.08%PRS 61.4
-
CSI 2.4rCSI 2.63%PRS 58.8
-
CSI 2.38rCSI 4.9%PRS 46.48
-
CSI 2.36rCSI 48.11%PRS 46.21
-
CSI 2.32rCSI 7.42%PRS 52.31
-
CSI 2.26rCSI 6.44%PRS 53.37
-
CSI 2.26rCSI 5.16%PRS 52.14
-
CSI 2.25rCSI 6.51%PRS 45.25
-
CSI 2.25rCSI 45.71%PRS 47.57
-
CSI 2.23rCSI 4.99%PRS 38.37
-
CSI 2.21rCSI 5.68%PRS 55.35
-
CSI 2.2rCSI 53.13%PRS 37.83
-
CSI 2.19rCSI 9.66%PRS 46.63
-
CSI 2.19rCSI 2.71%PRS 51.04
-
CSI 2.06rCSI 1.68%PRS 55.43
-
CSI 2.04rCSI 7.99%PRS 60.59
-
CSI 2.02rCSI 48.43%PRS 36.94
-
CSI 2.02rCSI 14.4%PRS 56.1
-
CSI 1.96rCSI 3.82%PRS 57.56
-
CSI 1.96rCSI 9.68%PRS 66.49
-
CSI 1.94rCSI 3.1%PRS 58.96
-
CSI 0.6rCSI 3.8%PRS 51.2%
-
CSI 0.6rCSI 1.1%PRS 65.6%
-
CSI 0.7rCSI 5.6%PRS 42.2%
-
CSI 0.7rCSI 4.5%PRS 52.2%
-
CSI 0.7rCSI 3.4%PRS 53.4%
-
CSI 0.7rCSI 5.4%PRS 51.6%
-
CSI 0.8rCSI 3.9%PRS 66.6%
-
CSI 0.8rCSI 2.3%PRS 68.8%
-
CSI 0.9rCSI 3.7%PRS 66.3%
-
CSI 0.9rCSI 6.0%PRS 58.2%
-
CSI 1.0rCSI 3.9%PRS 55.3%
-
CSI 1.0rCSI 2.8%PRS 52.7%
-
CSI 1.1rCSI 3.5%PRS 42.6%
-
CSI 1.1rCSI 2.9%PRS 62.8%
-
CSI 1.2rCSI 2.8%PRS 42.9%
-
CSI 1.2rCSI 2.9%PRS 63.3%
-
CSI 1.3rCSI 5.9%PRS 54.2%
-
CSI 1.4rCSI 4.5%PRS 41.2%
-
CSI 1.4rCSI 2.3%PRS 45.0%
-
CSI 1.5rCSI 2.1%PRS 57.6%
-
CSI 1.5rCSI 5.7%PRS 70.7%
-
CSI 1.5rCSI 3.3%PRS 52.8%
-
CSI 1.5rCSI 4.4%PRS 69.5%
-
CSI 1.6rCSI 2.5%PRS 56.6%
-
CSI 1.6rCSI 4.9%PRS 41.5%
-
CSI 1.6rCSI 2.0%PRS 57.0%
-
CSI 1.6rCSI 25.7%PRS 59.6%
-
CSI 1.7rCSI 4.3%PRS 73.5%
-
CSI 1.7rCSI 5.5%PRS 56.2%
-
CSI 1.7rCSI 9.1%PRS 61.5%
-
CSI 1.8rCSI 6.9%PRS 46.7%
-
CSI 1.8rCSI 2.8%PRS 55.7%
-
CSI 1.8rCSI 1.9%PRS 58.3%
-
CSI 1.8rCSI 4.5%PRS 53.0%
-
CSI 1.8rCSI 3.2%PRS 63.5%
-
CSI 1.9rCSI 2.5%PRS 60.6%
-
CSI 1.9rCSI 14.0%PRS 72.8%
-
CSI 1.9rCSI 8.3%PRS 74.6%
-
CSI 1.9rCSI 4.1%PRS 63.6%
-
CSI 1.9rCSI 3.4%PRS 48.1%
-
CSI 1.9rCSI 3.0%PRS 63.2%
-
CSI 1.9rCSI 5.3%PRS 50.9%
-
CSI 1.9rCSI 10.9%PRS 40.6%
-
CSI 1.9rCSI 4.9%PRS 63.6%
-
CSI 1.9rCSI 3.1%PRS 59.0%
-
CSI 2.0rCSI 9.7%PRS 66.5%
-
CSI 2.0rCSI 3.8%PRS 57.6%
-
CSI 2.0rCSI 14.4%PRS 56.1%
-
CSI 2.0rCSI 48.4%PRS 36.9%
-
CSI 2.0rCSI 8.0%PRS 60.6%
-
CSI 2.1rCSI 1.7%PRS 55.4%
-
CSI 2.2rCSI 2.7%PRS 51.0%
-
CSI 2.2rCSI 9.7%PRS 46.6%
-
CSI 2.2rCSI 53.1%PRS 37.8%
-
CSI 2.2rCSI 5.7%PRS 55.4%
-
CSI 2.2rCSI 5.0%PRS 38.4%
-
CSI 2.3rCSI 45.7%PRS 47.6%
-
CSI 2.3rCSI 6.5%PRS 45.3%
-
CSI 2.3rCSI 5.2%PRS 52.1%
-
CSI 2.3rCSI 6.4%PRS 53.4%
-
CSI 2.3rCSI 7.4%PRS 52.3%
-
CSI 2.4rCSI 48.1%PRS 46.2%
-
CSI 2.4rCSI 4.9%PRS 46.5%
-
CSI 2.4rCSI 2.6%PRS 58.8%
-
CSI 2.4rCSI 3.1%PRS 61.4%
-
CSI 2.5rCSI 4.3%PRS 45.2%
-
CSI 2.5rCSI 6.4%PRS 53.1%
-
CSI 2.5rCSI 4.4%PRS 53.9%
-
CSI 2.5rCSI 4.2%PRS 37.6%
-
CSI 2.5rCSI 12.0%PRS 54.5%
-
CSI 2.7rCSI 23.0%PRS 53.1%
-
CSI 2.7rCSI 8.0%PRS 65.5%
-
CSI 2.7rCSI 4.4%PRS 39.7%
-
CSI 2.7rCSI 4.0%PRS 58.9%
-
CSI 2.8rCSI 29.6%PRS 54.1%
-
CSI 2.8rCSI 14.3%PRS 57.3%
-
CSI 2.9rCSI 40.7%PRS 46.6%
-
CSI 2.9rCSI 2.3%PRS 56.3%
-
CSI 3.0rCSI 2.8%PRS 55.0%
-
CSI 3.0rCSI 3.7%PRS 53.3%
-
CSI 3.1rCSI 6.7%PRS 43.7%
-
CSI 3.1rCSI 3.3%PRS 51.8%
-
CSI 3.1rCSI 4.3%PRS 49.4%
-
CSI 3.2rCSI 23.2%PRS 42.1%
-
CSI 3.2rCSI 9.3%PRS 58.5%
-
CSI 3.2rCSI 18.7%PRS 39.0%
-
CSI 3.2rCSI 15.4%PRS 54.2%
-
CSI 3.2rCSI 6.4%PRS 53.1%
-
CSI 3.2rCSI 2.7%PRS 53.9%
-
CSI 3.3rCSI 4.4%PRS 55.9%
-
CSI 3.3rCSI 3.6%PRS 53.7%
-
CSI 3.4rCSI 3.3%PRS 55.4%
-
CSI 3.5rCSI 12.9%PRS 47.3%
-
CSI 3.7rCSI 6.5%PRS 36.6%
-
CSI 3.7rCSI 7.8%PRS 52.3%
-
CSI 3.8rCSI 9.1%PRS 36.4%
-
CSI 3.8rCSI 23.6%PRS 47.0%
-
CSI 3.8rCSI 9.9%PRS 54.3%
-
CSI 3.8rCSI 7.7%PRS 35.5%
-
CSI 3.8rCSI 6.3%PRS 44.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2137350654
Symbol: P2R3A_HUMAN
Name: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8392071
Title: Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing.
PubMed ID: 8392071
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
Sequence Information:
- Length: 1150
- Mass: 130278
- Checksum: 97A31BA4206518A3
- Sequence:
MAATYRLVVS TVNHYSSVVI DRRFEQAIHY CTGTCHTFTH GIDCIVVHHS VCADLLHIPV SQFKDADLNS MFLPHENGLS SAEGDYPQQA FTGIPRVKRG STFQNTYNLK DIAGEAISFA SGKIKEFSFE KLKNSNHAAY RKGRKVKSDS FNRRSVDLDL LCGHYNNDGN APSFGLLRSS SVEEKPLSHR NSLDTNLTSM FLQNFSEEDL VTQILEKHKI DNFSSGTDIK MCLDILLKCS EDLKKCTDII KQCIKKKSGS SISEGSGNDT ISSSETVYMN VMTRLASYLK KLPFEFMQSG NNEALDLTEL ISNMPSLQLT PFSPVFGTEQ PPKYEDVVQL SASDSGRFQT IELQNDKPNS RKMDTVQSIP NNSTNSLYNL EVNDPRTLKA VQVQSQSLTM NPLENVSSDD LMETLYIEEE SDGKKALDKG QKTENGPSHE LLKVNEHRAE FPEHATHLKK CPTPMQNEIG KIFEKSFVNL PKEDCKSKVS KFEEGDQRDF TNSSSQEEID KLLMDLESFS QKMETSLREP LAKGKNSNFL NSHSQLTGQT LVDLEPKSKV SSPIEKVSPS CLTRIIETNG HKIEEEDRAL LLRILESIED FAQELVECKS SRGSLSQEKE MMQILQETLT TSSQANLSVC RSPVGDKAKD TTSAVLIQQT PEVIKIQNKP EKKPGTPLPP PATSPSSPRP LSPVPHVNNV VNAPLSINIP RFYFPEGLPD TCSNHEQTLS RIETAFMDIE EQKADIYEMG KIAKVCGCPL YWKAPMFRAA GGEKTGFVTA QSFIAMWRKL LNNHHDDASK FICLLAKPNC SSLEQEDFIP LLQDVVDTHP GLTFLKDAPE FHSRYITTVI QRIFYTVNRS WSGKITSTEI RKSNFLQTLA LLEEEEDINQ ITDYFSYEHF YVIYCKFWEL DTDHDLYISQ ADLSRYNDQA SSSRIIERIF SGAVTRGKTI QKEGRMSYAD FVWFLISEED KRNPTSIEYW FRCMDVDGDG VLSMYELEYF YEEQCERMEA MGIEPLPFHD LLCQMLDLVK PAVDGKITLR DLKRCRMAHI FYDTFFNLEK YLDHEQRDPF AVQKDVENDG PEPSDWDRFA AEEYETLVAE ESAQAQFQEG FEDYETDEPA SPSEFGNKSN KILSASLPEK CGKLQSVDEE