SOX6 | ENSG00000110693 | NCBI 55553

Details for: SOX6

Gene ID: 55553

Symbol: SOX6

Ensembl ID: ENSG00000110693

Description: SRY-box transcription factor 6

Associated with

Deactivation of the beta-catenin transactivating complex
(R-HSA-3769402)
Signaling by wnt
(R-HSA-195721)
Signal transduction
(R-HSA-162582)
Tcf dependent signaling in response to wnt
(R-HSA-201681)
Brain development
(GO:0007420)
Cartilage condensation
(GO:0001502)
Cartilage development
(GO:0051216)
Cell fate commitment
(GO:0045165)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Central nervous system development
(GO:0007417)
Chondrocyte differentiation
(GO:0002062)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity
(GO:0001217)
Dna binding
(GO:0003677)
Muscle organ development
(GO:0007517)
Negative regulation of cardiac muscle cell differentiation
(GO:2000726)
Negative regulation of dna-templated transcription
(GO:0045892)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cartilage development
(GO:0061036)
Positive regulation of chondrocyte differentiation
(GO:0032332)
Positive regulation of mesenchymal stem cell differentiation
(GO:2000741)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Spinal cord oligodendrocyte cell differentiation
(GO:0021529)
Transcription cis-regulatory region binding
(GO:0000976)

Other Information

Proteins

SOX6_HUMAN

Genular Protein ID: 358693696

Symbol: SOX6_HUMAN

Name: N/A

UniProtKB Accession Codes:

P35712 Q86VX7 Q9BXQ3 Q9BXQ4 Q9BXQ5 Q9H0I8

Database IDs:

Citations:

PubMed ID: 11255018

Title: Cloning, characterization and chromosome mapping of the human SOX6 gene.

PubMed ID: 11255018

DOI: 10.1016/s0378-1119(01)00346-8

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1614875

Title: A conserved family of genes related to the testis determining gene, SRY.

PubMed ID: 1614875

DOI: 10.1093/nar/20.11.2887

PubMed ID: 16442531

Title: Repression of SOX6 transcriptional activity by SUMO modification.

PubMed ID: 16442531

DOI: 10.1016/j.febslet.2006.01.031

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 32442410

Title: De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas.

PubMed ID: 32442410

DOI: 10.1016/j.ajhg.2020.04.015

Sequence Information:

Length: 828
Mass: 91921
Checksum: 38CA781528C839CF
Sequence:

MSSKQATSPF ACAADGEDAM TQDLTSREKE EGSDQHVASH LPLHPIMHNK PHSEELPTLV 
STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRDRE IMTSVTFGTP 
ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 
PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 
QQQLLQQQHK INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 
DNYPVQFIPS TMAAAAASGL SPLQLQKGHV SHPQINQRLK GLSDRFGRNL DTFEHGGGHS 
YNHKQIEQLY AAQLASMQVS PGAKMPSTPQ PPNTAGTVSP TGIKNEKRGT SPVTQVKDEA 
AAQPLNLSSR PKTAEPVKSP TSPTQNLFPA SKTSPVNLPN KSSIPSPIGG SLGRGSSLDI 
LSSLNSPALF GDQDTVMKAI QEARKMREQI QREQQQQQPH GVDGKLSSIN NMGLNSCRNE 
KERTRFENLG PQLTGKSNED GKLGPGVIDL TRPEDAEGSK AMNGSAAKLQ QYYCWPTGGA 
TVAEARVYRD ARGRASSEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN ISKILGSRWK 
SMSNQEKQPY YEEQARLSKI HLEKYPNYKY KPRPKRTCIV DGKKLRIGEY KQLMRSRRQE 
MRQFFTVGQQ PQIPITTGTG VVYPGAITMA TTTPSPQMTS DCSSTSASPE PSLPVIQSTY 
GMKTDGGSLA GNEMINGEDE MEMYDDYEDD PKSDYSSENE APEAVSAN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SOX6

Associated with

Other Information

Cloning, characterization and chromosome mapping of the human SOX6 gene. PubMed ID: 11255018

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A conserved family of genes related to the testis determining gene, SRY. PubMed ID: 1614875

Repression of SOX6 transcriptional activity by SUMO modification. PubMed ID: 16442531

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas. PubMed ID: 32442410