ITGB3BP | ENSG00000142856 | NCBI 23421

Details for: ITGB3BP

Gene ID: 23421

Symbol: ITGB3BP

Ensembl ID: ENSG00000142856

Description: integrin subunit beta 3 binding protein

Associated with

Amplification of signal from the kinetochores
(R-HSA-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-HSA-141444)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cell cycle checkpoints
(R-HSA-69620)
Cell death signalling via nrage, nrif and nade
(R-HSA-204998)
Chromosome maintenance
(R-HSA-73886)
Death receptor signaling
(R-HSA-73887)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-HSA-606279)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
Mitotic spindle checkpoint
(R-HSA-69618)
M phase
(R-HSA-68886)
Nrif signals cell death from the nucleus
(R-HSA-205043)
Nucleosome assembly
(R-HSA-774815)
P75 ntr receptor-mediated signalling
(R-HSA-193704)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Apoptotic process
(GO:0006915)
Cell adhesion
(GO:0007155)
Cell division
(GO:0051301)
Cenp-a containing chromatin assembly
(GO:0034080)
Chromosome segregation
(GO:0007059)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Inner kinetochore
(GO:0000939)
Membrane
(GO:0016020)
Negative regulation of epithelial cell apoptotic process
(GO:1904036)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Signal transduction
(GO:0007165)

Other Information

Proteins

Centromere protein R

Genular Protein ID: 2292231475

Symbol: CENPR_HUMAN

Name: Centromere protein R

UniProtKB Accession Codes:

Q13352 B2R7D8 Q13353 Q5RJ42 Q5RJ44 Q5RJ45 Q7KYX2 Q96CD5 Q9UKB6

Database IDs:

Citations:

PubMed ID: 7593198

Title: Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit.

PubMed ID: 7593198

DOI: 10.1083/jcb.131.3.807

PubMed ID: 10490654

Title: NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors.

PubMed ID: 10490654

DOI: 10.1128/mcb.19.10.7191

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11864709

Title: Novel alternatively spliced form of beta(3)-endonexin.

PubMed ID: 11864709

DOI: 10.1016/s0049-3848(01)00405-4

PubMed ID: 9182673

Title: Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail.

PubMed ID: 9182673

DOI: 10.1083/jcb.137.6.1433

PubMed ID: 10673397

Title: Beta3-endonexin as a novel inhibitor of cyclin A-associated kinase.

PubMed ID: 10673397

DOI: 10.1006/bbrc.1999.2007

PubMed ID: 11713274

Title: Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation.

PubMed ID: 11713274

DOI: 10.1128/mcb.21.24.8371-8384.2001

PubMed ID: 12244126

Title: Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor.

PubMed ID: 12244126

DOI: 10.1242/jcs.00081

PubMed ID: 15082778

Title: The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells.

PubMed ID: 15082778

DOI: 10.1128/mcb.24.9.3838-3848.2004

PubMed ID: 15254226

Title: Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator.

PubMed ID: 15254226

DOI: 10.1128/mcb.24.15.6581-6591.2004

PubMed ID: 16622420

Title: The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

PubMed ID: 16622420

DOI: 10.1038/ncb1396

PubMed ID: 16622419

Title: The human CENP-A centromeric nucleosome-associated complex.

PubMed ID: 16622419

DOI: 10.1038/ncb1397

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

Length: 177
Mass: 20194
Checksum: C0A6FD5A56E98D43
Sequence:

MPVKRSLKLD GLLEENSFDP SKITRKKSVI TYSPTTGTCQ MSLFASPTSS EEQKHRNGLS 
NEKRKKLNHP SLTESKESTT KDNDEFMMLL SKVEKLSEEI MEIMQNLSSI QALEGSRELE 
NLIGISCASH FLKREMQKTK ELMTKVNKQK LFEKSTGLPH KASRHLDSYE FLKAILN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ITGB3BP

Associated with

Other Information

Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit. PubMed ID: 7593198

NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors. PubMed ID: 10490654

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Novel alternatively spliced form of beta(3)-endonexin. PubMed ID: 11864709

Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail. PubMed ID: 9182673

Beta3-endonexin as a novel inhibitor of cyclin A-associated kinase. PubMed ID: 10673397

Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation. PubMed ID: 11713274

Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor. PubMed ID: 12244126

The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells. PubMed ID: 15082778

Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator. PubMed ID: 15254226

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. PubMed ID: 16622420

The human CENP-A centromeric nucleosome-associated complex. PubMed ID: 16622419

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733