Details for: PRSS23
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 48.58rCSI 62.31%PRS 92.9
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CSI 32.16rCSI 37.3%PRS 91.75
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CSI 30.51rCSI 66.61%PRS 93.47
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CSI 30.29rCSI 44.37%PRS 87.56
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CSI 27.86rCSI 37.91%PRS 95.28
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CSI 26.36rCSI 27.51%PRS 90.56
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CSI 25.35rCSI 24.93%PRS 93.05
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CSI 25.16rCSI 26.07%PRS 92.92
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CSI 23.32rCSI 17.74%PRS 98.26
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CSI 22.66rCSI 22.62%PRS 86.22
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CSI 21.47rCSI 31.41%PRS 94.43
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CSI 21.43rCSI 41.67%PRS 92.74
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CSI 20.32rCSI 62.61%PRS 92.83
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CSI 18.9rCSI 39.22%PRS 89.91
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CSI 17.85rCSI 81.9%PRS 93.07
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CSI 17.54rCSI 70.1%PRS 94.12
-
CSI 16.01rCSI 35.44%PRS 91.44
-
CSI 13.98rCSI 25.4%PRS 95.46
-
CSI 12.32rCSI 60.71%PRS 94.55
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CSI 12.2rCSI 19.62%PRS 80.43
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CSI 12.13rCSI 13%PRS 92.76
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CSI 12.02rCSI 32.79%PRS 93.89
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CSI 11.78rCSI 15.12%PRS 84.11
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CSI 11.55rCSI 26.92%PRS 96.18
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CSI 11.41rCSI 13.62%PRS 97.95
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CSI 11.28rCSI 11.81%PRS 93.12
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CSI 11.22rCSI 10.45%PRS 92.77
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CSI 10.79rCSI 61.91%PRS 94.01
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CSI 10.74rCSI 17.06%PRS 95.18
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CSI 10.55rCSI 13%PRS 91.03
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CSI 10.16rCSI 69.74%PRS 94.25
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CSI 10.07rCSI 13.95%PRS 88.46
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CSI 10.04rCSI 42.2%PRS 93
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CSI 9.91rCSI 22.22%PRS 79.83
-
CSI 9.7rCSI 68.44%PRS 91.99
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CSI 9.54rCSI 41.22%PRS 93.36
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CSI 9.48rCSI 25.01%PRS 94.82
-
CSI 9.45rCSI 69.13%PRS 95.34
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CSI 9.27rCSI 6.18%PRS 96.24
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CSI 9.16rCSI 36.48%PRS 94.23
-
CSI 9.13rCSI 25.09%PRS 94.16
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CSI 9.12rCSI 11.34%PRS 77.27
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CSI 9.07rCSI 17.3%PRS 96.01
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CSI 8.97rCSI 14.33%PRS 93.48
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CSI 8.89rCSI 9.29%PRS 89.23
-
CSI 8.75rCSI 32.77%PRS 87.47
-
CSI 8.65rCSI 17.13%PRS 92.69
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CSI 8.64rCSI 13.75%PRS 87.25
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CSI 8.45rCSI 13.35%PRS 92.29
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CSI 8.3rCSI 23.59%PRS 88.22
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CSI 8.15rCSI 11.56%PRS 89.53
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CSI 8.07rCSI 7.77%PRS 90.03
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CSI 8.05rCSI 10.24%PRS 94.5
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CSI 7.49rCSI 7.22%PRS 87.65
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CSI 7.3rCSI 17.39%PRS 91.62
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CSI 7.02rCSI 5.7%PRS 90.83
-
CSI 6.95rCSI 12.03%PRS 86.5
-
CSI 6.89rCSI 22.04%PRS 90.32
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CSI 6.88rCSI 9.2%PRS 88.96
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CSI 6.75rCSI 10.19%PRS 95
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CSI 6.74rCSI 5.98%PRS 89.14
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CSI 6.68rCSI 8.88%PRS 93.91
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CSI 6.62rCSI 9.05%PRS 94.18
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CSI 6.6rCSI 5.69%PRS 90.96
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CSI 6.44rCSI 4.99%PRS 93.51
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CSI 6.39rCSI 20.74%PRS 89.79
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CSI 6.39rCSI 10.35%PRS 85.93
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CSI 6.19rCSI 6.48%PRS 89.38
-
CSI 5.99rCSI 20.25%PRS 86.42
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CSI 5.98rCSI 30.62%PRS 93.32
-
CSI 5.86rCSI 12.89%PRS 93.62
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CSI 5.81rCSI 8.37%PRS 93.77
-
CSI 5.8rCSI 23.41%PRS 92.06
-
CSI 5.74rCSI 62.46%PRS 93.79
-
CSI 5.65rCSI 16.35%PRS 93.5
-
CSI 5.57rCSI 9.93%PRS 94.79
-
CSI 5.56rCSI 7.43%PRS 94.31
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CSI 5.47rCSI 9.64%PRS 93.88
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CSI 5.46rCSI 13.28%PRS 77.35
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CSI 5.32rCSI 7.59%PRS 91.53
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CSI 5.11rCSI 7.49%PRS 95.76
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CSI 5.09rCSI 6.56%PRS 80.58
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CSI 5.06rCSI 11.18%PRS 81.76
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CSI 5.01rCSI 55.99%PRS 94.88
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CSI 4.99rCSI 44.23%PRS 94.79
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CSI 4.98rCSI 5.45%PRS 93
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CSI 4.81rCSI 7.88%PRS 85.1
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CSI 4.7rCSI 11.9%PRS 93.5
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CSI 4.59rCSI 4.34%PRS 89.45
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CSI 4.58rCSI 3.8%PRS 92.25
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CSI 4.54rCSI 3.59%PRS 85.08
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CSI 4.49rCSI 5.47%PRS 94.48
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CSI 4.38rCSI 10.45%PRS 85.91
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CSI 4.34rCSI 4.62%PRS 93.44
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CSI 4.19rCSI 11.2%PRS 86.66
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CSI 4.01rCSI 11.61%PRS 90.76
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CSI 3.94rCSI 5.42%PRS 98.04
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CSI 3.88rCSI 13.77%PRS 92.62
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CSI 3.84rCSI 9.73%PRS 85.89
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CSI 3.82rCSI 20.07%PRS 93.03
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CSI 0.6rCSI 5.5%PRS 95.1%
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CSI 0.7rCSI 5.2%PRS 85.7%
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CSI 0.8rCSI 18.0%PRS 77.2%
-
CSI 0.8rCSI 2.9%PRS 79.7%
-
CSI 1.0rCSI 3.1%PRS 88.2%
-
CSI 1.0rCSI 5.9%PRS 94.3%
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CSI 1.1rCSI 5.3%PRS 97.4%
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CSI 1.1rCSI 2.6%PRS 93.0%
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CSI 1.1rCSI 12.0%PRS 88.0%
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CSI 1.1rCSI 4.0%PRS 95.0%
-
CSI 1.2rCSI 5.9%PRS 86.5%
-
CSI 1.2rCSI 7.6%PRS 93.9%
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CSI 1.3rCSI 13.9%PRS 93.2%
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CSI 1.3rCSI 31.2%PRS 77.4%
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CSI 1.5rCSI 8.1%PRS 96.1%
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CSI 1.5rCSI 8.7%PRS 79.9%
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CSI 1.5rCSI 2.3%PRS 95.9%
-
CSI 1.6rCSI 4.3%PRS 92.2%
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CSI 1.6rCSI 8.8%PRS 94.8%
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CSI 1.7rCSI 4.3%PRS 93.9%
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CSI 1.7rCSI 13.5%PRS 89.2%
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CSI 1.7rCSI 4.2%PRS 92.5%
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CSI 1.8rCSI 13.8%PRS 92.1%
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CSI 1.8rCSI 2.1%PRS 86.4%
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CSI 1.9rCSI 3.1%PRS 79.5%
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CSI 1.9rCSI 2.6%PRS 89.8%
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CSI 2.0rCSI 4.6%PRS 84.9%
-
CSI 2.0rCSI 3.6%PRS 90.1%
-
CSI 2.0rCSI 7.3%PRS 77.6%
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CSI 2.1rCSI 5.1%PRS 92.1%
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CSI 2.1rCSI 40.0%PRS 95.0%
-
CSI 2.1rCSI 5.5%PRS 90.9%
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CSI 2.2rCSI 6.9%PRS 82.5%
-
CSI 2.2rCSI 12.2%PRS 87.7%
-
CSI 2.2rCSI 14.7%PRS 93.6%
-
CSI 2.4rCSI 2.8%PRS 79.5%
-
CSI 2.4rCSI 58.1%PRS 94.2%
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CSI 2.4rCSI 7.9%PRS 89.1%
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CSI 2.5rCSI 4.4%PRS 78.9%
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CSI 2.5rCSI 5.9%PRS 93.4%
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CSI 2.7rCSI 5.3%PRS 88.3%
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CSI 2.7rCSI 6.9%PRS 86.9%
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CSI 2.8rCSI 3.8%PRS 84.5%
-
CSI 2.8rCSI 7.9%PRS 88.0%
-
CSI 2.8rCSI 13.2%PRS 94.4%
-
CSI 2.9rCSI 2.6%PRS 83.3%
-
CSI 2.9rCSI 13.2%PRS 94.4%
-
CSI 2.9rCSI 8.1%PRS 89.1%
-
CSI 3.0rCSI 15.8%PRS 91.3%
-
CSI 3.0rCSI 11.4%PRS 79.7%
-
CSI 3.1rCSI 7.0%PRS 85.5%
-
CSI 3.2rCSI 18.6%PRS 92.8%
-
CSI 3.2rCSI 15.4%PRS 92.4%
-
CSI 3.3rCSI 8.5%PRS 89.1%
-
CSI 3.3rCSI 3.7%PRS 97.3%
-
CSI 3.5rCSI 7.0%PRS 85.8%
-
CSI 3.5rCSI 16.8%PRS 88.3%
-
CSI 3.7rCSI 11.5%PRS 80.8%
-
CSI 3.7rCSI 3.4%PRS 97.6%
-
CSI 3.7rCSI 6.0%PRS 88.7%
-
CSI 3.8rCSI 9.0%PRS 88.8%
-
CSI 3.8rCSI 14.5%PRS 85.5%
-
CSI 3.8rCSI 15.6%PRS 95.4%
-
CSI 3.8rCSI 20.1%PRS 93.0%
-
CSI 3.8rCSI 9.7%PRS 85.9%
-
CSI 3.9rCSI 13.8%PRS 92.6%
-
CSI 3.9rCSI 5.4%PRS 98.0%
-
CSI 4.0rCSI 11.6%PRS 90.8%
-
CSI 4.2rCSI 11.2%PRS 86.7%
-
CSI 4.3rCSI 4.6%PRS 93.4%
-
CSI 4.4rCSI 10.5%PRS 85.9%
-
CSI 4.5rCSI 5.5%PRS 94.5%
-
CSI 4.5rCSI 3.6%PRS 85.1%
-
CSI 4.6rCSI 3.8%PRS 92.3%
-
CSI 4.6rCSI 4.3%PRS 89.5%
-
CSI 4.7rCSI 11.9%PRS 93.5%
-
CSI 4.8rCSI 7.9%PRS 85.1%
-
CSI 5.0rCSI 5.5%PRS 93.0%
-
CSI 5.0rCSI 44.2%PRS 94.8%
-
CSI 5.0rCSI 56.0%PRS 94.9%
-
CSI 5.1rCSI 11.2%PRS 81.8%
-
CSI 5.1rCSI 6.6%PRS 80.6%
-
CSI 5.1rCSI 7.5%PRS 95.8%
-
CSI 5.3rCSI 7.6%PRS 91.5%
-
CSI 5.5rCSI 13.3%PRS 77.4%
-
CSI 5.5rCSI 9.6%PRS 93.9%
-
CSI 5.6rCSI 7.4%PRS 94.3%
-
CSI 5.6rCSI 9.9%PRS 94.8%
-
CSI 5.7rCSI 16.4%PRS 93.5%
-
CSI 5.7rCSI 62.5%PRS 93.8%
-
CSI 5.8rCSI 23.4%PRS 92.1%
-
CSI 5.8rCSI 8.4%PRS 93.8%
-
CSI 5.9rCSI 12.9%PRS 93.6%
-
CSI 6.0rCSI 30.6%PRS 93.3%
-
CSI 6.0rCSI 20.3%PRS 86.4%
-
CSI 6.2rCSI 6.5%PRS 89.4%
-
CSI 6.4rCSI 10.4%PRS 85.9%
-
CSI 6.4rCSI 20.7%PRS 89.8%
-
CSI 6.4rCSI 5.0%PRS 93.5%
-
CSI 6.6rCSI 5.7%PRS 91.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2263884523
Symbol: PRS23_HUMAN
Name: Serine protease 23
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
Sequence Information:
- Length: 383
- Mass: 43001
- Checksum: 46EB6C11ABFD5E8F
- Sequence:
MAGIPGLLFL LFFLLCAVGQ VSPYSAPWKP TWPAYRLPVV LPQSTLNLAK PDFGAEAKLE VSSSCGPQCH KGTPLPTYEE AKQYLSYETL YANGSRTETQ VGIYILSSSG DGAQHRDSGS SGKSRRKRQI YGYDSRFSIF GKDFLLNYPF STSVKLSTGC TGTLVAEKHV LTAAHCIHDG KTYVKGTQKL RVGFLKPKFK DGGRGANDST SAMPEQMKFQ WIRVKRTHVP KGWIKGNAND IGMDYDYALL ELKKPHKRKF MKIGVSPPAK QLPGGRIHFS GYDNDRPGNL VYRFCDVKDE TYDLLYQQCD AQPGASGSGV YVRMWKRQQQ KWERKIIGIF SGHQWVDMNG SPQDFNVAVR ITPLKYAQIC YWIKGNYLDC REG