Details for: SUN2

Gene ID: 25777

Symbol: SUN2

Ensembl ID: ENSG00000100242

Description: Sad1 and UNC84 domain containing 2

Associated with

Other Information

Genular Protein ID: 3175562925

Symbol: SUN2_HUMAN

Name: SUN domain-containing protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10818110

Title: A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion.

PubMed ID: 10818110

DOI: 10.1074/jbc.m909600199

PubMed ID: 17132086

Title: Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome.

PubMed ID: 17132086

DOI: 10.1089/dna.2006.25.554

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10375507

Title: UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.

PubMed ID: 10375507

DOI: 10.1242/dev.126.14.3171

PubMed ID: 12393179

Title: Isolation of differentially expressed genes in human heart tissues.

PubMed ID: 12393179

DOI: 10.1016/s0925-4439(02)00171-0

PubMed ID: 12239280

Title: A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate.

PubMed ID: 12239280

DOI: 10.1074/mcp.m200010-mcp200

PubMed ID: 12958361

Title: Nuclear membrane proteins with potential disease links found by subtractive proteomics.

PubMed ID: 12958361

DOI: 10.1126/science.1088176

PubMed ID: 15082709

Title: Sun2 is a novel mammalian inner nuclear membrane protein.

PubMed ID: 15082709

DOI: 10.1074/jbc.m313157200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17724119

Title: Functional association of Sun1 with nuclear pore complexes.

PubMed ID: 17724119

DOI: 10.1083/jcb.200704108

PubMed ID: 18845190

Title: Sun1 forms immobile macromolecular assemblies at the nuclear envelope.

PubMed ID: 18845190

DOI: 10.1016/j.bbamcr.2008.09.001

PubMed ID: 18396275

Title: Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

PubMed ID: 18396275

DOI: 10.1016/j.yexcr.2008.02.022

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21391237

Title: TMEM43 mutations in Emery-Dreifuss muscular dystrophy-related myopathy.

PubMed ID: 21391237

DOI: 10.1002/ana.22338

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26244732

Title: A disulfide bond is required for the transmission of forces through SUN-KASH complexes.

PubMed ID: 26244732

DOI: 10.1016/j.bpj.2015.06.057

PubMed ID: 22632968

Title: LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

PubMed ID: 22632968

DOI: 10.1016/j.cell.2012.03.046

PubMed ID: 22945352

Title: Structural insights into SUN-KASH complexes across the nuclear envelope.

PubMed ID: 22945352

DOI: 10.1038/cr.2012.126

PubMed ID: 22170055

Title: Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.

PubMed ID: 22170055

DOI: 10.1074/jbc.m111.304543

Sequence Information:

  • Length: 717
  • Mass: 80311
  • Checksum: CCF43C118E935E84
  • Sequence:
  • MSRRSQRLTR YSQGDDDGSS SSGGSSVAGS QSTLFKDSPL RTLKRKSSNM KRLSPAPQLG 
    PSSDAHTSYY SESLVHESWF PPRSSLEELH GDANWGEDLR VRRRRGTGGS ESSRASGLVG 
    RKATEDFLGS SSGYSSEDDY VGYSDVDQQS SSSRLRSAVS RAGSLLWMVA TSPGRLFRLL 
    YWWAGTTWYR LTTAASLLDV FVLTRRFSSL KTFLWFLLPL LLLTCLTYGA WYFYPYGLQT 
    FHPALVSWWA AKDSRRPDEG WEARDSSPHF QAEQRVMSRV HSLERRLEAL AAEFSSNWQK 
    EAMRLERLEL RQGAPGQGGG GGLSHEDTLA LLEGLVSRRE AALKEDFRRE TAARIQEELS 
    ALRAEHQQDS EDLFKKIVRA SQESEARIQQ LKSEWQSMTQ ESFQESSVKE LRRLEDQLAG 
    LQQELAALAL KQSSVAEEVG LLPQQIQAVR DDVESQFPAW ISQFLARGGG GRVGLLQREE 
    MQAQLRELES KILTHVAEMQ GKSAREAAAS LSLTLQKEGV IGVTEEQVHH IVKQALQRYS 
    EDRIGLADYA LESGGASVIS TRCSETYETK TALLSLFGIP LWYHSQSPRV ILQPDVHPGN 
    CWAFQGPQGF AVVRLSARIR PTAVTLEHVP KALSPNSTIS SAPKDFAIFG FDEDLQQEGT 
    LLGKFTYDQD GEPIQTFHFQ APTMATYQVV ELRILTNWGH PEYTCIYRFR VHGEPAH

Genular Protein ID: 598384615

Symbol: B4E2A6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 752
  • Mass: 83965
  • Checksum: 10EEE401D14DA067
  • Sequence:
  • MVSPPSAGQR LRGVPVWAAG AFRFSSGEES TSHLIMSRRS QRLTRYSQGD DDGSSSSGGS 
    SVAGSQSTLF KDSPLRTLKR KSSNMKRLSP APQLGPSSDA HTSYYSESLV HESWFPPRSS 
    LEELHGDANW GEDLRVRRRR GTGGSESSRA SGLVGRKATE DFLGSSSGYS SEDDYVGYSD 
    VDQQSSSSRL RSAVSRAGSL LWMVATSPGR LFRLLYWWAG STWYRLTTAA SLLDVFVLTR 
    RFSSLKTFLW FLLPLLLLTC LTYGAWYFYP YGLQTFHPAL VSWWAAKDSR RPDEGWEARD 
    SSPHFQAEQR VMSRVHSLER RLEALAAEFS SNWQKEAMRL ERLELRQGAP GQGGGGGLSH 
    EDTLALLEGL VSRREAALKE DFRRETAARI QEELSALRAE HQQDSEDLFK KIVRASQESE 
    ARIQQLKSEW QSMTQESFQE SSVKELRRLE DQLAGLQQEL AALALKQSSV AEEVGLLPQQ 
    IQAVRDDVES QFPAWISQFL ARGGGGRVGL LQREEMQAQL RELESKILTH VAEMQGKSAR 
    EAAASLSLTL QKEGVIGVTE EQVHHIVKQA LQRYSEDRIG LADYALESGG ASVISTRCSE 
    TYETKTALLS LFGIPLWYHS QSPRVILQPD VHPGNCWAFQ GPQGFAVVRL SARIRPTAVT 
    LEHVPKALSP NSTISSAPKD FAIFGFDEDL QQEGTLLGKF TYDQDGEPIQ TFHFQAPTMA 
    TYQVVELRIL TNWGHPEYTC IYRFRVHGEP AH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.