Details for: CELF1

Gene ID: 10658

Symbol: CELF1

Ensembl ID: ENSG00000149187

Description: CUGBP Elav-like family member 1

Associated with

Other Information

Genular Protein ID: 3290153310

Symbol: CELF1_HUMAN

Name: CUGBP Elav-like family member 1

UniProtKB Accession Codes:

Q92879 B4E2U5 D3DQS0 F8W940 Q4LE52 Q9NP83 Q9NR06

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 3 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EPD 1 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 26 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NIAGADS 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 8 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 18 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8948631

Title: Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy.

PubMed ID: 8948631

DOI: 10.1093/nar/24.22.4407

PubMed ID: 10893231

Title: A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.

PubMed ID: 10893231

DOI: 10.1074/jbc.m003083200

PubMed ID: 11686919

Title: Coexpression of the CUG-binding protein reduces DM protein kinase expression in COS cells.

PubMed ID: 11686919

DOI: 10.1093/oxfordjournals.jbchem.a003022

PubMed ID: 11707455

Title: c-Jun ARE targets mRNA deadenylation by an EDEN-BP (embryo deadenylation element-binding protein)-dependent pathway.

PubMed ID: 11707455

DOI: 10.1074/jbc.m109362200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10536163

Title: CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms.

PubMed ID: 10536163

DOI: 10.1093/nar/27.22.4517

PubMed ID: 11124939

Title: RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1.

PubMed ID: 11124939

DOI: 10.1074/jbc.m005960200

PubMed ID: 11158314

Title: The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing.

PubMed ID: 11158314

DOI: 10.1128/mcb.21.4.1285-1296.2001

PubMed ID: 12799066

Title: A functional deadenylation assay identifies human CUG-BP as a deadenylation factor.

PubMed ID: 12799066

DOI: 10.1016/s0248-4900(03)00010-8

PubMed ID: 12649496

Title: Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein.

PubMed ID: 12649496

DOI: 10.1261/rna.2191903

PubMed ID: 14726956

Title: Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.

PubMed ID: 14726956

DOI: 10.1038/sj.emboj.7600052

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 16946708

Title: Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing.

PubMed ID: 16946708

DOI: 10.1038/sj.emboj.7601296

PubMed ID: 16862542

Title: ETR-3 represses Tau exons 2/3 inclusion, a splicing event abnormally enhanced in myotonic dystrophy type I.

PubMed ID: 16862542

DOI: 10.1002/jnr.20980

PubMed ID: 16601207

Title: CUG-BP binds to RNA substrates and recruits PARN deadenylase.

PubMed ID: 16601207

DOI: 10.1261/rna.59606

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28431233

Title: A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

PubMed ID: 28431233

DOI: 10.1016/j.molcel.2017.03.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 20947024

Title: Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1.

PubMed ID: 20947024

DOI: 10.1016/j.str.2010.06.018

Sequence Information:

  • Length: 486
  • Mass: 52063
  • Checksum: C4C13D772273A01D
  • Sequence:
    • MNGTLDHPDQ PDLDAIKMFV GQVPRTWSEK DLRELFEQYG AVYEINVLRD RSQNPPQSKG 
CCFVTFYTRK AALEAQNALH NMKVLPGMHH PIQMKPADSE KNNAVEDRKL FIGMISKKCT 
ENDIRVMFSS FGQIEECRIL RGPDGLSRGC AFVTFTTRAM AQTAIKAMHQ AQTMEGCSSP 
MVVKFADTQK DKEQKRMAQQ LQQQMQQISA ASVWGNLAGL NTLGPQYLAL YLQLLQQTAS 
SGNLNTLSSL HPMGGLNAMQ LQNLAALAAA ASAAQNTPSG TNALTTSSSP LSVLTSSGSS 
PSSSSSNSVN PIASLGALQT LAGATAGLNV GSLAGMAALN GGLGSSGLSN GTGSTMEALT 
QAYSGIQQYA AAALPTLYNQ NLLTQQSIGA AGSQKEGPEG ANLFIYHLPQ EFGDQDLLQM 
FMPFGNVVSA KVFIDKQTNL SKCFGFVSYD NPVSAQAAIQ SMNGFQIGMK RLKVQLKRSK 
NDSKPY

Genular Protein ID: 1520219164

Symbol: G5EA30_HUMAN

Name: N/A

UniProtKB Accession Codes:

G5EA30

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 3 GO 11 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 5 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 514
  • Mass: 55143
  • Checksum: 31E7DF974827F9B3
  • Sequence:
    • MAAFKLDFLP EMMVDHCSLN SSPVSKKMNG TLDHPDQPDL DAIKMFVGQV PRTWSEKDLR 
ELFEQYGAVY EINVLRDRSQ NPPQSKGCCF VTFYTRKAAL EAQNALHNMK VLPGMHHPIQ 
MKPADSEKNN AVEDRKLFIG MISKKCTEND IRVMFSSFGQ IEECRILRGP DGLSRGCAFV 
TFTTRAMAQT AIKAMHQAQT MEGCSSPMVV KFADTQKDKE QKRMAQQLQQ QMQQISAASV 
WGNLAGLNTL GPQYLALYLQ LLQQTASSGN LNTLSSLHPM GGLNAMQLQN LAALAAAASA 
AQNTPSGTNA LTTSSSPLSV LTSSAGSSPS SSSSNSVNPI ASLGALQTLA GATAGLNVGS 
LAGMAALNGG LGSSGLSNGT GSTMEALTQA YSGIQQYAAA ALPTLYNQNL LTQQSIGAAG 
SQKEGPEGAN LFIYHLPQEF GDQDLLQMFM PFGNVVSAKV FIDKQTNLSK CFGFVSYDNP 
VSAQAAIQSM NGFQIGMKRL KVQLKRSKND SKPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.