Details for: STXBP3
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 13.48rCSI 19.53%PRS 61.65
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CSI 12.06rCSI 21.66%PRS 39.04
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CSI 6.42rCSI 15.45%PRS 63.71
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CSI 6.35rCSI 27.56%PRS 60.9
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CSI 5.86rCSI 4.38%PRS 60.15
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CSI 5.37rCSI 14.18%PRS 53.29
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CSI 5.12rCSI 14.82%PRS 37.03
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CSI 4.94rCSI 5.29%PRS 43.5
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CSI 4.72rCSI 3.78%PRS 66.92
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CSI 4.63rCSI 11.91%PRS 47.99
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CSI 4.3rCSI 7.37%PRS 54.77
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CSI 4.13rCSI 10.48%PRS 36.27
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CSI 3.81rCSI 5.82%PRS 54.7
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CSI 3.5rCSI 2.64%PRS 57.85
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CSI 3.32rCSI 2.23%PRS 55.94
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CSI 3.22rCSI 13.35%PRS 54.65
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CSI 3.17rCSI 4.03%PRS 50.95
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CSI 3.08rCSI 19.25%PRS 38.14
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CSI 2.74rCSI 8.14%PRS 56.86
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CSI 2.71rCSI 1.6%PRS 60.81
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CSI 2.68rCSI 6.08%PRS 50.85
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CSI 2.65rCSI 2.55%PRS 36.38
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CSI 2.62rCSI 1.82%PRS 54.16
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CSI 2.53rCSI 5.56%PRS 59.94
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CSI 2.37rCSI 3.7%PRS 72.38
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CSI 2.37rCSI 1.99%PRS 50.35
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CSI 2.36rCSI 2.27%PRS 46.05
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CSI 2.28rCSI 5.46%PRS 60.92
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CSI 2.25rCSI 2.8%PRS 56.71
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CSI 2.21rCSI 1.64%PRS 39.1
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CSI 2.19rCSI 1.73%PRS 33.48
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CSI 2.15rCSI 5.18%PRS 55.56
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CSI 2.14rCSI 2.1%PRS 60.94
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CSI 2.13rCSI 2.91%PRS 50.49
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CSI 2.12rCSI 1.72%PRS 46.15
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CSI 2.08rCSI 7.78%PRS 38.66
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CSI 2.05rCSI 1.91%PRS 45.24
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CSI 2.04rCSI 2.4%PRS 60.99
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CSI 2.02rCSI 5.23%PRS 41.77
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CSI 2.01rCSI 2%PRS 39.82
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CSI 1.99rCSI 4.54%PRS 44.93
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CSI 1.95rCSI 1.87%PRS 69.59
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CSI 1.94rCSI 2.6%PRS 54
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CSI 1.91rCSI 6.93%PRS 64.81
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CSI 1.9rCSI 1.67%PRS 55.1
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CSI 1.89rCSI 3.61%PRS 62.17
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CSI 1.88rCSI 3.32%PRS 43.81
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CSI 1.87rCSI 1.34%PRS 58.51
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CSI 1.86rCSI 3.06%PRS 50.98
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CSI 1.85rCSI 2.94%PRS 38.69
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CSI 1.84rCSI 2.37%PRS 30.93
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CSI 1.84rCSI 5.27%PRS 63.4
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CSI 1.81rCSI 2.68%PRS 50.62
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CSI 1.8rCSI 1.46%PRS 46.12
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CSI 1.8rCSI 1.66%PRS 46.42
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CSI 1.79rCSI 1.25%PRS 47.35
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CSI 1.79rCSI 3.26%PRS 39.22
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CSI 1.79rCSI 4.34%PRS 29.16
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CSI 1.76rCSI 2.44%PRS 44.89
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CSI 1.75rCSI 7.14%PRS 42.79
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CSI 1.75rCSI 2.79%PRS 49.36
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CSI 1.75rCSI 8.36%PRS 44.11
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CSI 1.73rCSI 2.09%PRS 53.35
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CSI 1.73rCSI 2%PRS 35.87
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CSI 1.72rCSI 1.43%PRS 44.04
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CSI 1.71rCSI 6.9%PRS 44.02
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CSI 1.71rCSI 2.29%PRS 46.91
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CSI 1.68rCSI 2.57%PRS 46.06
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CSI 1.68rCSI 1.48%PRS 34.85
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CSI 1.68rCSI 3.38%PRS 35.58
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CSI 1.67rCSI 1.3%PRS 46.05
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CSI 1.67rCSI 2.28%PRS 48.13
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CSI 1.66rCSI 1.71%PRS 63.5
-
CSI 1.64rCSI 1.99%PRS 53.15
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CSI 1.63rCSI 1.54%PRS 46.27
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CSI 1.61rCSI 3.34%PRS 43.45
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CSI 1.59rCSI 2.34%PRS 56.73
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CSI 1.57rCSI 2.75%PRS 38.05
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CSI 1.55rCSI 2.78%PRS 43.93
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CSI 1.55rCSI 3.53%PRS 39.04
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CSI 1.54rCSI 1.92%PRS 28.49
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CSI 1.54rCSI 1.61%PRS 45.02
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CSI 1.53rCSI 1.34%PRS 50.49
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CSI 1.52rCSI 1.35%PRS 44.44
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CSI 1.51rCSI 1.14%PRS 49.02
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CSI 1.51rCSI 3.06%PRS 28.3
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CSI 1.5rCSI 2.39%PRS 39.5
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CSI 1.49rCSI 1.24%PRS 46.48
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CSI 1.49rCSI 1.03%PRS 58.43
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CSI 1.48rCSI 1.14%PRS 44.38
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CSI 1.47rCSI 2.09%PRS 42.54
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CSI 1.47rCSI 1.82%PRS 48.22
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CSI 1.46rCSI 1.53%PRS 42.63
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CSI 1.45rCSI 2.48%PRS 71.64
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CSI 1.45rCSI 1.26%PRS 49.24
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CSI 1.45rCSI 3.19%PRS 49.38
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CSI 1.43rCSI 3.42%PRS 55.89
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CSI 1.43rCSI 1.89%PRS 50.37
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CSI 1.39rCSI 1.26%PRS 60.35
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CSI 1.37rCSI 1.59%PRS 39.89
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CSI 0.1rCSI 0.8%PRS 57.5%
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CSI 0.2rCSI 3.5%PRS 30.3%
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CSI 0.2rCSI 3.9%PRS 29.5%
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CSI 0.2rCSI 0.9%PRS 28.9%
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CSI 0.3rCSI 2.1%PRS 33.3%
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CSI 0.3rCSI 1.6%PRS 69.4%
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CSI 0.3rCSI 1.9%PRS 69.7%
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CSI 0.3rCSI 1.6%PRS 45.1%
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CSI 0.3rCSI 1.0%PRS 33.5%
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CSI 0.3rCSI 2.5%PRS 33.8%
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CSI 0.4rCSI 3.2%PRS 65.4%
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CSI 0.5rCSI 1.7%PRS 30.9%
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CSI 0.5rCSI 1.5%PRS 34.6%
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CSI 0.5rCSI 1.6%PRS 42.6%
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CSI 0.5rCSI 0.8%PRS 36.3%
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CSI 0.6rCSI 1.0%PRS 55.8%
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CSI 0.6rCSI 0.9%PRS 32.1%
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CSI 0.6rCSI 1.8%PRS 53.1%
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CSI 0.6rCSI 1.1%PRS 47.6%
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CSI 0.6rCSI 1.9%PRS 31.2%
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CSI 0.6rCSI 3.4%PRS 53.7%
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CSI 0.7rCSI 1.1%PRS 36.3%
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CSI 0.7rCSI 2.9%PRS 39.1%
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CSI 0.7rCSI 1.0%PRS 43.3%
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CSI 0.7rCSI 1.9%PRS 48.0%
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CSI 0.7rCSI 1.6%PRS 62.8%
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CSI 0.7rCSI 3.0%PRS 44.2%
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CSI 0.7rCSI 1.2%PRS 56.2%
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CSI 0.8rCSI 3.7%PRS 57.5%
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CSI 0.8rCSI 1.5%PRS 63.2%
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CSI 0.8rCSI 2.1%PRS 38.5%
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CSI 0.8rCSI 3.0%PRS 38.8%
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CSI 0.8rCSI 1.8%PRS 34.0%
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CSI 0.8rCSI 0.8%PRS 51.3%
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CSI 0.8rCSI 4.1%PRS 56.5%
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CSI 0.9rCSI 5.2%PRS 31.4%
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CSI 0.9rCSI 1.4%PRS 42.3%
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CSI 1.0rCSI 1.2%PRS 41.5%
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CSI 1.0rCSI 2.7%PRS 63.0%
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CSI 1.0rCSI 3.7%PRS 66.0%
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CSI 1.0rCSI 1.2%PRS 30.0%
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CSI 1.0rCSI 1.5%PRS 46.6%
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CSI 1.0rCSI 1.4%PRS 48.2%
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CSI 1.0rCSI 2.2%PRS 42.9%
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CSI 1.0rCSI 2.9%PRS 62.1%
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CSI 1.0rCSI 1.5%PRS 47.5%
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CSI 1.0rCSI 2.7%PRS 50.4%
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CSI 1.0rCSI 3.4%PRS 34.0%
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CSI 1.1rCSI 1.0%PRS 42.2%
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CSI 1.1rCSI 1.8%PRS 30.1%
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CSI 1.1rCSI 2.9%PRS 54.2%
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CSI 1.1rCSI 1.6%PRS 37.0%
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CSI 1.1rCSI 3.1%PRS 45.4%
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CSI 1.1rCSI 2.1%PRS 35.5%
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CSI 1.1rCSI 1.5%PRS 58.6%
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CSI 1.1rCSI 2.9%PRS 67.9%
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CSI 1.2rCSI 2.6%PRS 30.8%
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CSI 1.2rCSI 2.1%PRS 29.1%
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CSI 1.2rCSI 1.0%PRS 55.0%
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CSI 1.2rCSI 2.9%PRS 43.6%
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CSI 1.2rCSI 1.8%PRS 52.6%
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CSI 1.2rCSI 0.9%PRS 62.5%
-
CSI 1.2rCSI 1.5%PRS 55.3%
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CSI 1.2rCSI 1.8%PRS 48.6%
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CSI 1.3rCSI 1.7%PRS 38.9%
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CSI 1.3rCSI 0.8%PRS 49.3%
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CSI 1.3rCSI 1.2%PRS 52.9%
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CSI 1.3rCSI 1.7%PRS 41.7%
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CSI 1.3rCSI 1.6%PRS 59.0%
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CSI 1.3rCSI 3.0%PRS 47.6%
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CSI 1.3rCSI 3.3%PRS 44.6%
-
CSI 1.3rCSI 2.8%PRS 55.2%
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CSI 1.3rCSI 1.9%PRS 48.0%
-
CSI 1.3rCSI 1.5%PRS 49.1%
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CSI 1.3rCSI 2.3%PRS 36.4%
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CSI 1.3rCSI 2.9%PRS 52.1%
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CSI 1.3rCSI 1.9%PRS 54.1%
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CSI 1.3rCSI 1.5%PRS 49.4%
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CSI 1.4rCSI 2.0%PRS 41.4%
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CSI 1.4rCSI 3.4%PRS 53.8%
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CSI 1.4rCSI 1.6%PRS 39.9%
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CSI 1.4rCSI 1.3%PRS 60.4%
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CSI 1.4rCSI 1.9%PRS 50.4%
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CSI 1.4rCSI 3.4%PRS 55.9%
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CSI 1.5rCSI 3.2%PRS 49.4%
-
CSI 1.5rCSI 1.3%PRS 49.2%
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CSI 1.5rCSI 2.5%PRS 71.6%
-
CSI 1.5rCSI 1.5%PRS 42.6%
-
CSI 1.5rCSI 1.8%PRS 48.2%
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CSI 1.5rCSI 2.1%PRS 42.5%
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CSI 1.5rCSI 1.1%PRS 44.4%
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CSI 1.5rCSI 1.0%PRS 58.4%
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CSI 1.5rCSI 1.2%PRS 46.5%
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CSI 1.5rCSI 2.4%PRS 39.5%
-
CSI 1.5rCSI 3.1%PRS 28.3%
-
CSI 1.5rCSI 1.1%PRS 49.0%
-
CSI 1.5rCSI 1.4%PRS 44.4%
-
CSI 1.5rCSI 1.3%PRS 50.5%
-
CSI 1.5rCSI 1.6%PRS 45.0%
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CSI 1.5rCSI 1.9%PRS 28.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 4276039821
Symbol: STXB3_HUMAN
Name: Syntaxin-binding protein 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8824310
Title: A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants.
PubMed ID: 8824310
PubMed ID: 10194441
Title: Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion.
PubMed ID: 10194441
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 592
- Mass: 67764
- Checksum: AAFA268E2D328EC7
- Sequence:
MAPPVAERGL KSVVWQKIKA TVFDDCKKEG EWKIMLLDEF TTKLLASCCK MTDLLEEGIT VVENIYKNRE PVRQMKALYF ITPTSKSVDC FLHDFASKSE NKYKAAYIYF TDFCPDNLFN KIKASCSKSI RRCKEINISF IPHESQVYTL DVPDAFYYCY SPDPGNAKGK DAIMETMADQ IVTVCATLDE NPGVRYKSKP LDNASKLAQL VEKKLEDYYK IDEKSLIKGK THSQLLIIDR GFDPVSTVLH ELTFQAMAYD LLPIENDTYK YKTDGKEKEA ILEEEDDLWV RIRHRHIAVV LEEIPKLMKE ISSTKKATEG KTSLSALTQL MKKMPHFRKQ ITKQVVHLNL AEDCMNKFKL NIEKLCKTEQ DLALGTDAEG QKVKDSMRVL LPVLLNKNHD NCDKIRAILL YIFSINGTTE ENLDRLIQNV KIENESDMIR NWSYLGVPIV PQSQQGKPLR KDRSAEETFQ LSRWTPFIKD IMEDAIDNRL DSKEWPYCSQ CPAVWNGSGA VSARQKPRAN YLEDRKNGSK LIVFVIGGIT YSEVRCAYEV SQAHKSCEVI IGSTHVLTPK KLLDDIKMLN KPKDKVSLIK DE