Associated with
Other Information
Genular Protein ID: 2122137382
Symbol: CBX5_HUMAN
Name: Chromobox protein homolog 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8505380
Title: Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity.
PubMed ID: 8505380
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8663349
Title: Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1.
PubMed ID: 8663349
PubMed ID: 9169472
Title: Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR.
PubMed ID: 9169472
PubMed ID: 10460410
Title: Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells.
PubMed ID: 10460410
PubMed ID: 11313457
Title: Common properties of nuclear protein SP100 and TIF1alpha chromatin factor: role of SUMO modification.
PubMed ID: 11313457
PubMed ID: 11242053
Title: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
PubMed ID: 11242053
DOI: 10.1038/35065132
PubMed ID: 15502821
Title: A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.
PubMed ID: 15502821
DOI: 10.1038/ncb1187
PubMed ID: 15882967
Title: The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.
PubMed ID: 15882967
PubMed ID: 15864296
Title: Dissociation of heterochromatin protein 1 from lamin B receptor induced by human polyomavirus agnoprotein: role in nuclear egress of viral particles.
PubMed ID: 15864296
PubMed ID: 15899859
Title: In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation.
PubMed ID: 15899859
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19617346
Title: Physical and functional interaction between heterochromatin protein 1alpha and the RNA-binding protein heterogeneous nuclear ribonucleoprotein U.
PubMed ID: 19617346
PubMed ID: 19710015
Title: The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.
PubMed ID: 19710015
PubMed ID: 19783980
Title: JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.
PubMed ID: 19783980
DOI: 10.1038/nature08448
PubMed ID: 19666599
Title: Human BAHD1 promotes heterochromatic gene silencing.
PubMed ID: 19666599
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20850016
Title: Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
PubMed ID: 20850016
PubMed ID: 19880879
Title: ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1.
PubMed ID: 19880879
PubMed ID: 25750265
Title: Retraction: 'ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1'.
PubMed ID: 25750265
PubMed ID: 20562864
Title: Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.
PubMed ID: 20562864
DOI: 10.1038/ncb2075
PubMed ID: 20498703
Title: Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10.
PubMed ID: 20498703
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21346195
Title: Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
PubMed ID: 21346195
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23542155
Title: Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway.
PubMed ID: 23542155
DOI: 10.1038/nsmb.2532
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25906157
Title: A novel role of PRR14 in the regulation of skeletal myogenesis.
PubMed ID: 25906157
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 28977666
Title: CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.
PubMed ID: 28977666
DOI: 10.1093/nar/gkx711
PubMed ID: 32051553
Title: The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.
PubMed ID: 32051553
PubMed ID: 21047797
Title: Recognition and specificity determinants of the human cbx chromodomains.
PubMed ID: 21047797
PubMed ID: 20042602
Title: The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.
PubMed ID: 20042602
Sequence Information:
- Length: 191
- Mass: 22225
- Checksum: 16FFC476367093B1
- Sequence:
MGKKTKRTAD SSSSEDEEEY VVEKVLDRRV VKGQVEYLLK WKGFSEEHNT WEPEKNLDCP ELISEFMKKY KKMKEGENNK PREKSESNKR KSNFSNSADD IKSKKKREQS NDIARGFERG LEPEKIIGAT DSCGDLMFLM KWKDTDEADL VLAKEANVKC PQIVIAFYEE RLTWHAYPED AENKEKETAK S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.