Details for: ARPC5L
Gene ID: 81873
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ARPC5L
Ensembl ID: ENSG00000136950
Description: actin related protein 2/3 complex subunit 5 like
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 39.74rCSI 26.48%PRS 62.34
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CSI 35.05rCSI 27.57%PRS 40.68
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CSI 32.05rCSI 30.85%PRS 35.71
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CSI 30.14rCSI 46.58%PRS 33.14
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CSI 29.33rCSI 36.81%PRS 43.66
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CSI 28.09rCSI 24.32%PRS 38.53
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CSI 22.67rCSI 16.97%PRS 48.95
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CSI 21.57rCSI 16.18%PRS 69.35
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CSI 18.49rCSI 40.84%PRS 25.66
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CSI 16.06rCSI 52.11%PRS 38.72
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CSI 15.04rCSI 17.44%PRS 45.75
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CSI 14.44rCSI 41.23%PRS 50.18
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CSI 14.21rCSI 12.48%PRS 39.56
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CSI 13.64rCSI 18.74%PRS 55.58
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CSI 13.42rCSI 11.25%PRS 39.83
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CSI 13.41rCSI 19.8%PRS 51.24
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CSI 12.99rCSI 25.26%PRS 36.36
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CSI 11.7rCSI 41.07%PRS 51.22
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CSI 11.18rCSI 12.8%PRS 58.01
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CSI 10.66rCSI 15.59%PRS 37.23
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CSI 10.12rCSI 13.79%PRS 63.56
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CSI 9.84rCSI 22.05%PRS 22.84
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CSI 9.82rCSI 24.94%PRS 32.7
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CSI 9.41rCSI 15.24%PRS 34.18
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CSI 9.28rCSI 17.88%PRS 64.97
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CSI 8.96rCSI 8.64%PRS 27.03
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CSI 8.93rCSI 16.91%PRS 70.4
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CSI 8.76rCSI 11.64%PRS 38.55
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CSI 8.49rCSI 18.08%PRS 49.82
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CSI 8.48rCSI 11.75%PRS 41.51
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CSI 8.48rCSI 9.55%PRS 50.43
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CSI 8.18rCSI 8.55%PRS 35.18
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CSI 7.82rCSI 17.47%PRS 40.59
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CSI 7.63rCSI 15.12%PRS 62.63
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CSI 7.18rCSI 13.7%PRS 51.22
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CSI 7.14rCSI 35.21%PRS 45.34
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CSI 6.94rCSI 6.92%PRS 30.09
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CSI 6.9rCSI 30.37%PRS 30.23
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CSI 6.87rCSI 8.5%PRS 31.31
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CSI 6.61rCSI 5.34%PRS 35.36
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CSI 6.61rCSI 5.86%PRS 34.5
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CSI 6.49rCSI 6.78%PRS 35.51
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CSI 6.29rCSI 21.25%PRS 46.24
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CSI 6.26rCSI 18.67%PRS 59.48
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CSI 6.18rCSI 5.43%PRS 26.05
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CSI 5.98rCSI 7.45%PRS 45.82
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CSI 5.88rCSI 12.2%PRS 33.94
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CSI 5.85rCSI 5.41%PRS 54.89
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CSI 5.77rCSI 6.78%PRS 38.65
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CSI 5.75rCSI 16.64%PRS 56.02
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CSI 5.47rCSI 7%PRS 72.3
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CSI 5.38rCSI 7.95%PRS 39.3
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CSI 5.35rCSI 7.01%PRS 75.72
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CSI 5.28rCSI 6.78%PRS 33.39
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CSI 5.25rCSI 4.96%PRS 36.12
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CSI 5.09rCSI 3.01%PRS 47.98
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CSI 5rCSI 13.06%PRS 45.27
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CSI 4.92rCSI 6.44%PRS 47.23
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CSI 4.9rCSI 3.42%PRS 36.73
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CSI 4.78rCSI 11.34%PRS 40.74
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CSI 4.75rCSI 3.57%PRS 37.6
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CSI 4.58rCSI 4.5%PRS 37.13
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CSI 4.57rCSI 8.1%PRS 23.23
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CSI 4.52rCSI 7.28%PRS 45.36
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CSI 4.46rCSI 7.05%PRS 35.59
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CSI 4.36rCSI 3.13%PRS 46.39
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CSI 4.34rCSI 3.59%PRS 35.64
-
CSI 4.19rCSI 18.08%PRS 52.16
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CSI 4.18rCSI 3.49%PRS 60.26
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CSI 4.14rCSI 4.22%PRS 46.81
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CSI 4.09rCSI 4.29%PRS 32.65
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CSI 4.03rCSI 11.6%PRS 53.47
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CSI 3.9rCSI 3.6%PRS 36.08
-
CSI 3.89rCSI 17.85%PRS 57.55
-
CSI 3.86rCSI 5.99%PRS 45.53
-
CSI 3.84rCSI 2.98%PRS 34.62
-
CSI 3.76rCSI 2.61%PRS 46.64
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CSI 3.72rCSI 3.26%PRS 44.19
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CSI 3.68rCSI 3.09%PRS 51.21
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CSI 3.67rCSI 15.94%PRS 51.55
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CSI 3.61rCSI 10.35%PRS 50.67
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CSI 3.61rCSI 4.93%PRS 37.68
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CSI 3.54rCSI 3.5%PRS 73.38
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CSI 3.5rCSI 7.22%PRS 43.69
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CSI 3.49rCSI 5.55%PRS 44.02
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CSI 3.42rCSI 2.74%PRS 55.61
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CSI 3.41rCSI 4.12%PRS 41.53
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CSI 3.41rCSI 7.51%PRS 38.86
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CSI 3.35rCSI 2.49%PRS 47.32
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CSI 3.35rCSI 3.11%PRS 34.74
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CSI 3.24rCSI 9.57%PRS 39.44
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CSI 3.24rCSI 32%PRS 66.18
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CSI 3.18rCSI 3.32%PRS 68.06
-
CSI 3.11rCSI 3.25%PRS 36.99
-
CSI 3.09rCSI 73.99%PRS 66.18
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CSI 3.06rCSI 4.88%PRS 37.96
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CSI 3.05rCSI 17.98%PRS 23.43
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CSI 3.05rCSI 17.72%PRS 46.47
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CSI 3.02rCSI 3.6%PRS 54.14
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CSI 2.97rCSI 20.38%PRS 55.1
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CSI 0.1rCSI 2.1%PRS 90.2%
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CSI 0.2rCSI 3.7%PRS 57.8%
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CSI 0.2rCSI 3.7%PRS 74.4%
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CSI 0.2rCSI 1.3%PRS 47.3%
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CSI 0.3rCSI 1.9%PRS 54.0%
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CSI 0.3rCSI 4.1%PRS 63.6%
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CSI 0.3rCSI 1.2%PRS 54.1%
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CSI 0.3rCSI 5.8%PRS 64.3%
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CSI 0.3rCSI 8.1%PRS 80.4%
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CSI 0.3rCSI 1.0%PRS 23.3%
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CSI 0.3rCSI 3.4%PRS 81.1%
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CSI 0.3rCSI 1.3%PRS 50.9%
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CSI 0.4rCSI 1.9%PRS 73.6%
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CSI 0.4rCSI 2.9%PRS 55.4%
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CSI 0.4rCSI 3.9%PRS 63.4%
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CSI 0.4rCSI 1.5%PRS 53.2%
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CSI 0.4rCSI 0.6%PRS 44.7%
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CSI 0.5rCSI 2.4%PRS 50.0%
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CSI 0.5rCSI 2.7%PRS 51.4%
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CSI 0.5rCSI 0.5%PRS 41.2%
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CSI 0.6rCSI 7.7%PRS 79.0%
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CSI 0.6rCSI 1.4%PRS 47.4%
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CSI 0.6rCSI 1.8%PRS 25.2%
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CSI 0.6rCSI 2.1%PRS 49.1%
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CSI 0.6rCSI 1.0%PRS 27.4%
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CSI 0.7rCSI 1.5%PRS 32.4%
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CSI 0.7rCSI 1.5%PRS 44.7%
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CSI 0.7rCSI 2.8%PRS 57.3%
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CSI 0.7rCSI 5.2%PRS 63.1%
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CSI 0.7rCSI 8.0%PRS 56.1%
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CSI 0.7rCSI 1.2%PRS 22.3%
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CSI 0.7rCSI 4.6%PRS 72.4%
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CSI 0.7rCSI 5.9%PRS 71.7%
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CSI 0.8rCSI 3.9%PRS 58.5%
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CSI 0.8rCSI 4.4%PRS 46.1%
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CSI 0.9rCSI 2.3%PRS 43.6%
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CSI 0.9rCSI 0.8%PRS 59.2%
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CSI 0.9rCSI 12.0%PRS 70.2%
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CSI 1.0rCSI 1.5%PRS 41.0%
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CSI 1.0rCSI 1.6%PRS 24.2%
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CSI 1.0rCSI 2.0%PRS 52.4%
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CSI 1.0rCSI 1.5%PRS 36.2%
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CSI 1.0rCSI 3.9%PRS 55.3%
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CSI 1.1rCSI 1.3%PRS 48.2%
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CSI 1.1rCSI 1.7%PRS 32.5%
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CSI 1.2rCSI 4.5%PRS 44.6%
-
CSI 1.2rCSI 2.1%PRS 51.3%
-
CSI 1.2rCSI 3.2%PRS 58.1%
-
CSI 1.2rCSI 1.5%PRS 41.9%
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CSI 1.2rCSI 1.8%PRS 42.9%
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CSI 1.3rCSI 1.5%PRS 33.6%
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CSI 1.3rCSI 2.6%PRS 57.9%
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CSI 1.3rCSI 5.6%PRS 33.6%
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CSI 1.3rCSI 3.0%PRS 62.6%
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CSI 1.3rCSI 4.9%PRS 23.1%
-
CSI 1.3rCSI 1.8%PRS 57.3%
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CSI 1.3rCSI 2.5%PRS 43.8%
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CSI 1.3rCSI 2.0%PRS 43.3%
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CSI 1.3rCSI 6.1%PRS 73.3%
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CSI 1.4rCSI 6.0%PRS 55.0%
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CSI 1.4rCSI 2.1%PRS 39.2%
-
CSI 1.4rCSI 2.4%PRS 55.8%
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CSI 1.4rCSI 7.8%PRS 41.8%
-
CSI 1.4rCSI 10.5%PRS 64.7%
-
CSI 1.5rCSI 1.1%PRS 52.9%
-
CSI 1.5rCSI 1.2%PRS 35.8%
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CSI 1.5rCSI 3.4%PRS 34.4%
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CSI 1.5rCSI 3.4%PRS 41.1%
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CSI 1.5rCSI 2.2%PRS 48.7%
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CSI 1.6rCSI 1.7%PRS 50.8%
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CSI 1.6rCSI 2.5%PRS 62.0%
-
CSI 1.6rCSI 2.4%PRS 44.8%
-
CSI 1.6rCSI 4.4%PRS 77.0%
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CSI 1.6rCSI 4.7%PRS 53.0%
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CSI 1.7rCSI 27.9%PRS 71.6%
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CSI 1.7rCSI 2.0%PRS 22.2%
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CSI 1.7rCSI 2.6%PRS 51.2%
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CSI 1.7rCSI 4.8%PRS 37.8%
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CSI 1.7rCSI 2.0%PRS 53.7%
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CSI 1.7rCSI 50.7%PRS 60.5%
-
CSI 1.7rCSI 1.4%PRS 55.8%
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CSI 1.7rCSI 3.3%PRS 58.8%
-
CSI 1.7rCSI 2.5%PRS 37.6%
-
CSI 1.7rCSI 1.4%PRS 24.8%
-
CSI 1.7rCSI 2.0%PRS 26.7%
-
CSI 1.7rCSI 8.1%PRS 59.7%
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CSI 1.7rCSI 8.7%PRS 44.7%
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CSI 1.8rCSI 3.2%PRS 29.6%
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CSI 1.8rCSI 5.0%PRS 49.8%
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CSI 1.8rCSI 1.5%PRS 33.4%
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CSI 1.8rCSI 1.7%PRS 49.4%
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CSI 1.8rCSI 2.4%PRS 23.1%
-
CSI 1.9rCSI 3.5%PRS 55.8%
-
CSI 1.9rCSI 1.5%PRS 49.9%
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CSI 1.9rCSI 3.3%PRS 43.3%
-
CSI 1.9rCSI 8.5%PRS 80.6%
-
CSI 1.9rCSI 2.5%PRS 39.4%
-
CSI 1.9rCSI 2.9%PRS 38.3%
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CSI 2.0rCSI 1.7%PRS 44.8%
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CSI 2.0rCSI 2.3%PRS 61.7%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 795438400
Symbol: ARP5L_HUMAN
Name: Actin-related protein 2/3 complex subunit 5-like protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 153
- Mass: 16941
- Checksum: D8E4772404300560
- Sequence:
MARNTLSSRF RRVDIDEFDE NKFVDEQEEA AAAAAEPGPD PSEVDGLLRQ GDMLRAFHAA LRNSPVNTKN QAVKERAQGV VLKVLTNFKS SEIEQAVQSL DRNGVDLLMK YIYKGFEKPT ENSSAVLLQW HEKALAVGGL GSIIRVLTAR KTV
Genular Protein ID: 3111543702
Symbol: B3KPC7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 153
- Mass: 16971
- Checksum: D8A5702473377517
- Sequence:
MARNTLSSRF RRVDIDEFDE NKFVDEQEEA AAAAAEPGPD PSEVDGLLRQ GDMLWAFHAA LRNSPVNTKN QAVKERAQGV VLKVLTNFKS SEIEQAVQSL DRNGVDLLMK YIYKGFEKPT ENSSAVLLQW HEKALAVGGL GSIIRVLTAR KTV