USP47 | ENSG00000170242 | NCBI 55031

Details for: USP47

Gene ID: 55031

Symbol: USP47

Ensembl ID: ENSG00000170242

Description: ubiquitin specific peptidase 47

Associated with

Deubiquitination
(R-HSA-5688426)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Ub-specific processing proteases
(R-HSA-5689880)
Base-excision repair
(GO:0006284)
Cellular response to uv
(GO:0034644)
Cysteine-type deubiquitinase activity
(GO:0004843)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Deubiquitinase activity
(GO:0101005)
Dna damage response
(GO:0006974)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Monoubiquitinated protein deubiquitination
(GO:0035520)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043154)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of g2/m transition of mitotic cell cycle
(GO:0010972)
Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
(GO:1902230)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of cell growth
(GO:0030307)
Protein binding
(GO:0005515)
Protein deubiquitination
(GO:0016579)
Proteolysis
(GO:0006508)
Response to xenobiotic stimulus
(GO:0009410)
Scf ubiquitin ligase complex
(GO:0019005)
Wd40-repeat domain binding
(GO:0071987)

Other Information

Proteins

Ubiquitin carboxyl-terminal hydrolase 47
Q68D97_HUMAN

Genular Protein ID: 1709050774

Symbol: UBP47_HUMAN

Name: Ubiquitin carboxyl-terminal hydrolase 47

UniProtKB Accession Codes:

Q96K76 B3KXF5 E9PM46 Q658U0 Q86Y73 Q8TEP6 Q9BWI0 Q9NWN1

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14715245

Title: Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

PubMed ID: 14715245

DOI: 10.1016/j.bbrc.2003.12.050

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19966869

Title: The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival.

PubMed ID: 19966869

DOI: 10.1038/onc.2009.430

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21362556

Title: USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA Polymerase beta.

PubMed ID: 21362556

DOI: 10.1016/j.molcel.2011.02.016

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 1375
Mass: 157311
Checksum: 1EDEAA9B5AFC97FE
Sequence:

MVPGEENQLV PKEDVFWRCR QNIFDEMKKK FLQIENAAEE PRVLCIIQDT TNSKTVNERI 
TLNLPASTPV RKLFEDVANK VGYINGTFDL VWGNGINTAD MAPLDHTSDK SLLDANFEPG 
KKNFLHLTDK DGEQPQILLE DSSAGEDSVH DRFIGPLPRE GSGGSTSDYV SQSYSYSSIL 
NKSETGYVGL VNQAMTCYLN SLLQTLFMTP EFRNALYKWE FEESEEDPVT SIPYQLQRLF 
VLLQTSKKRA IETTDVTRSF GWDSSEAWQQ HDVQELCRVM FDALEQKWKQ TEQADLINEL 
YQGKLKDYVR CLECGYEGWR IDTYLDIPLV IRPYGSSQAF ASVEEALHAF IQPEILDGPN 
QYFCERCKKK CDARKGLRFL HFPYLLTLQL KRFDFDYTTM HRIKLNDRMT FPEELDMSTF 
IDVEDEKSPQ TESCTDSGAE NEGSCHSDQM SNDFSNDDGV DEGICLETNS GTEKISKSGL 
EKNSLIYELF SVMVHSGSAA GGHYYACIKS FSDEQWYSFN DQHVSRITQE DIKKTHGGSS 
GSRGYYSSAF ASSTNAYMLI YRLKDPARNA KFLEVDEYPE HIKNLVQKER ELEEQEKRQR 
EIERNTCKIK LFCLHPTKQV MMENKLEVHK DKTLKEAVEM AYKMMDLEEV IPLDCCRLVK 
YDEFHDYLER SYEGEEDTPM GLLLGGVKST YMFDLLLETR KPDQVFQSYK PGEVMVKVHV 
VDLKAESVAA PITVRAYLNQ TVTEFKQLIS KAIHLPAETM RIVLERCYND LRLLSVSSKT 
LKAEGFFRSN KVFVESSETL DYQMAFADSH LWKLLDRHAN TIRLFVLLPE QSPVSYSKRT 
AYQKAGGDSG NVDDDCERVK GPVGSLKSVE AILEESTEKL KSLSLQQQQD GDNGDSSKST 
ETSDFENIES PLNERDSSAS VDNRELEQHI QTSDPENFQS EERSDSDVNN DRSTSSVDSD 
ILSSSHSSDT LCNADNAQIP LANGLDSHSI TSSRRTKANE GKKETWDTAE EDSGTDSEYD 
ESGKSRGEMQ YMYFKAEPYA ADEGSGEGHK WLMVHVDKRI TLAAFKQHLE PFVGVLSSHF 
KVFRVYASNQ EFESVRLNET LSSFSDDNKI TIRLGRALKK GEYRVKVYQL LVNEQEPCKF 
LLDAVFAKGM TVRQSKEELI PQLREQCGLE LSIDRFRLRK KTWKNPGTVF LDYHIYEEDI 
NISSNWEVFL EVLDGVEKMK SMSQLAVLSR RWKPSEMKLD PFQEVVLESS SVDELREKLS 
EISGIPLDDI EFAKGRGTFP CDISVLDIHQ DLDWNPKVST LNVWPLYICD DGAVIFYRDK 
TEELMELTDE QRNELMKKES SRLQKTGHRV TYSPRKEKAL KIYLDGAPNK DLTQD

Genular Protein ID: 1662329606

Symbol: Q68D97_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q68D97

Database IDs:

Sequence Information:

Length: 61
Mass: 7160
Checksum: 77EC9E9D540555CB
Sequence:

MVPGEENQLV PKEDVFWRCR QNIFDEMKKK FLQIENAAEE PRVLCIIQDT TNSKTVFMTG 
L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: USP47

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. PubMed ID: 14715245

A probability-based approach for high-throughput protein phosphorylation analysis and site localization. PubMed ID: 16964243

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival. PubMed ID: 19966869

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA Polymerase beta. PubMed ID: 21362556

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569