Details for: MZT2A
Gene ID: 653784
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: MZT2A
Ensembl ID: ENSG00000173272
Description: mitotic spindle organizing protein 2A
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 60.46rCSI 71%PRS 38.43
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CSI 56.6rCSI 45.76%PRS 35.18
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CSI 52.44rCSI 50.56%PRS 26.86
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CSI 47.69rCSI 49.85%PRS 35.05
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CSI 45.1rCSI 40.73%PRS 32.02
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CSI 44.57rCSI 46.69%PRS 36.77
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CSI 42.24rCSI 36.57%PRS 38.36
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CSI 37.42rCSI 34.08%PRS 49.21
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CSI 30.87rCSI 25.88%PRS 39.63
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CSI 29.07rCSI 24.1%PRS 33.25
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CSI 28.8rCSI 41.51%PRS 48.54
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CSI 28.66rCSI 27.59%PRS 35.53
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CSI 28.53rCSI 41.15%PRS 44.62
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CSI 26.63rCSI 38%PRS 37.36
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CSI 25.66rCSI 40.99%PRS 37.76
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CSI 24.62rCSI 24.57%PRS 29.94
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CSI 24.13rCSI 18.98%PRS 40.57
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CSI 22.84rCSI 28.66%PRS 43.47
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CSI 21.39rCSI 58.79%PRS 50.83
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CSI 21.29rCSI 25.55%PRS 33.39
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CSI 21.13rCSI 36.2%PRS 43.86
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CSI 21.04rCSI 27.97%PRS 38.39
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CSI 20.86rCSI 25.8%PRS 31.15
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CSI 20.12rCSI 15.5%PRS 33.2
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CSI 20.01rCSI 18.91%PRS 35.95
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CSI 19.97rCSI 20.83%PRS 35.37
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CSI 19.82rCSI 30.31%PRS 50.94
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CSI 19.1rCSI 45.4%PRS 47.22
-
CSI 17.72rCSI 31.25%PRS 43.06
-
CSI 17.31rCSI 11.51%PRS 39.15
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CSI 16.63rCSI 47.48%PRS 50
-
CSI 15.72rCSI 41.48%PRS 41.05
-
CSI 15.2rCSI 13.49%PRS 34.33
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CSI 14.76rCSI 32.96%PRS 40.44
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CSI 14.48rCSI 22.24%PRS 39.88
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CSI 14.02rCSI 10.41%PRS 47.15
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CSI 13.94rCSI 11.54%PRS 35.47
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CSI 13.94rCSI 14.6%PRS 32.53
-
CSI 13.92rCSI 12.24%PRS 25.9
-
CSI 13.72rCSI 11.45%PRS 60.12
-
CSI 13.71rCSI 12.59%PRS 41
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CSI 13.59rCSI 15.55%PRS 57.91
-
CSI 13.58rCSI 28.9%PRS 49.66
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CSI 13.17rCSI 13.64%PRS 40.15
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CSI 13.05rCSI 57.3%PRS 54.82
-
CSI 12.92rCSI 24.48%PRS 70.21
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CSI 12.64rCSI 44.35%PRS 51.07
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CSI 12.57rCSI 17.13%PRS 29.93
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CSI 12.48rCSI 42.21%PRS 46.01
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CSI 12.45rCSI 27.41%PRS 38.65
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CSI 12.27rCSI 9.54%PRS 49.71
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CSI 12.08rCSI 11.92%PRS 73.16
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CSI 11.96rCSI 18.56%PRS 45.32
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CSI 11.82rCSI 8.21%PRS 41.81
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CSI 11.78rCSI 12.31%PRS 67.9
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CSI 11.74rCSI 30.91%PRS 57.93
-
CSI 11.74rCSI 18.14%PRS 32.97
-
CSI 11.65rCSI 31.4%PRS 43.45
-
CSI 11.62rCSI 9.19%PRS 24.66
-
CSI 11.33rCSI 58.5%PRS 58.33
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CSI 10.93rCSI 7.68%PRS 60.22
-
CSI 10.83rCSI 20.48%PRS 59.49
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CSI 10.67rCSI 9.93%PRS 34.56
-
CSI 10.64rCSI 9.32%PRS 44.01
-
CSI 10.57rCSI 22.48%PRS 42.08
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CSI 10.48rCSI 56.56%PRS 49.82
-
CSI 10.48rCSI 19.63%PRS 26.5
-
CSI 10.44rCSI 7.84%PRS 37.46
-
CSI 10.41rCSI 16.86%PRS 34.05
-
CSI 10.36rCSI 9.58%PRS 54.74
-
CSI 10.31rCSI 16.89%PRS 27.36
-
CSI 10.17rCSI 8.27%PRS 35.63
-
CSI 10.16rCSI 14.07%PRS 41.34
-
CSI 10.04rCSI 8.04%PRS 55.45
-
CSI 9.79rCSI 22.31%PRS 34.2
-
CSI 9.71rCSI 20.04%PRS 43.5
-
CSI 9.69rCSI 13.25%PRS 38.83
-
CSI 9.61rCSI 31.18%PRS 38.56
-
CSI 9.55rCSI 10.15%PRS 50.65
-
CSI 9.42rCSI 27.01%PRS 50.48
-
CSI 9.32rCSI 6.49%PRS 46.52
-
CSI 9.27rCSI 29.75%PRS 43.35
-
CSI 9.24rCSI 14.12%PRS 43.13
-
CSI 9.18rCSI 15.12%PRS 39.74
-
CSI 9.12rCSI 11.6%PRS 39.4
-
CSI 9.11rCSI 36.26%PRS 50.66
-
CSI 9.07rCSI 48.8%PRS 51.13
-
CSI 8.94rCSI 19.79%PRS 32.25
-
CSI 8.85rCSI 6.64%PRS 69.25
-
CSI 8.78rCSI 8.62%PRS 49.23
-
CSI 8.19rCSI 12.94%PRS 35.42
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CSI 8.19rCSI 13.2%PRS 45.25
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CSI 8.14rCSI 35.83%PRS 30.07
-
CSI 8.13rCSI 7.14%PRS 39.39
-
CSI 8.04rCSI 13.76%PRS 55.67
-
CSI 7.95rCSI 15.78%PRS 34.93
-
CSI 7.9rCSI 5.67%PRS 46.25
-
CSI 7.85rCSI 10.9%PRS 34.85
-
CSI 7.75rCSI 7.15%PRS 35.93
-
CSI 7.59rCSI 10.42%PRS 55.4
-
CSI 0.2rCSI 4.4%PRS 64.9%
-
CSI 0.2rCSI 4.3%PRS 74.3%
-
CSI 0.2rCSI 5.3%PRS 90.0%
-
CSI 0.2rCSI 0.7%PRS 29.5%
-
CSI 0.3rCSI 7.6%PRS 75.9%
-
CSI 0.3rCSI 0.6%PRS 22.2%
-
CSI 0.4rCSI 2.1%PRS 47.1%
-
CSI 0.7rCSI 3.6%PRS 60.0%
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CSI 0.7rCSI 2.7%PRS 57.2%
-
CSI 0.7rCSI 10.7%PRS 63.6%
-
CSI 0.7rCSI 2.6%PRS 48.9%
-
CSI 0.7rCSI 1.1%PRS 32.2%
-
CSI 0.8rCSI 1.2%PRS 29.4%
-
CSI 0.8rCSI 1.2%PRS 24.0%
-
CSI 0.8rCSI 1.3%PRS 27.2%
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CSI 0.8rCSI 1.1%PRS 44.5%
-
CSI 0.8rCSI 3.7%PRS 73.2%
-
CSI 0.9rCSI 1.9%PRS 55.3%
-
CSI 0.9rCSI 2.8%PRS 35.2%
-
CSI 0.9rCSI 2.0%PRS 44.4%
-
CSI 1.0rCSI 2.6%PRS 76.9%
-
CSI 1.0rCSI 3.1%PRS 68.4%
-
CSI 1.0rCSI 2.4%PRS 27.2%
-
CSI 1.0rCSI 5.6%PRS 69.9%
-
CSI 1.1rCSI 1.2%PRS 38.4%
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CSI 1.2rCSI 6.2%PRS 76.1%
-
CSI 1.2rCSI 13.6%PRS 75.6%
-
CSI 1.2rCSI 8.4%PRS 63.0%
-
CSI 1.3rCSI 5.8%PRS 80.4%
-
CSI 1.3rCSI 2.4%PRS 63.2%
-
CSI 1.3rCSI 12.7%PRS 79.3%
-
CSI 1.4rCSI 2.1%PRS 37.1%
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CSI 1.4rCSI 3.2%PRS 49.0%
-
CSI 1.5rCSI 3.7%PRS 82.7%
-
CSI 1.6rCSI 2.8%PRS 51.1%
-
CSI 1.6rCSI 2.2%PRS 45.9%
-
CSI 1.6rCSI 5.0%PRS 23.2%
-
CSI 1.6rCSI 6.2%PRS 55.1%
-
CSI 1.6rCSI 8.0%PRS 45.1%
-
CSI 1.7rCSI 4.8%PRS 37.8%
-
CSI 1.7rCSI 4.4%PRS 67.7%
-
CSI 1.7rCSI 11.4%PRS 70.9%
-
CSI 1.8rCSI 3.4%PRS 64.7%
-
CSI 1.8rCSI 31.5%PRS 74.2%
-
CSI 1.8rCSI 5.3%PRS 28.0%
-
CSI 1.8rCSI 13.3%PRS 64.5%
-
CSI 1.9rCSI 20.4%PRS 56.0%
-
CSI 1.9rCSI 1.4%PRS 52.7%
-
CSI 1.9rCSI 5.5%PRS 37.6%
-
CSI 1.9rCSI 4.8%PRS 42.1%
-
CSI 1.9rCSI 6.5%PRS 26.1%
-
CSI 2.0rCSI 31.3%PRS 63.4%
-
CSI 2.1rCSI 3.6%PRS 21.4%
-
CSI 2.1rCSI 6.3%PRS 59.3%
-
CSI 2.1rCSI 63.5%PRS 60.4%
-
CSI 2.1rCSI 9.4%PRS 33.5%
-
CSI 2.2rCSI 3.4%PRS 40.9%
-
CSI 2.3rCSI 2.4%PRS 46.7%
-
CSI 2.3rCSI 8.0%PRS 72.8%
-
CSI 2.3rCSI 6.5%PRS 49.6%
-
CSI 2.3rCSI 1.4%PRS 47.7%
-
CSI 2.3rCSI 4.2%PRS 29.5%
-
CSI 2.5rCSI 9.6%PRS 53.9%
-
CSI 2.6rCSI 2.0%PRS 34.4%
-
CSI 2.6rCSI 3.9%PRS 36.0%
-
CSI 2.6rCSI 60.6%PRS 57.7%
-
CSI 2.7rCSI 5.4%PRS 52.3%
-
CSI 2.7rCSI 6.9%PRS 32.6%
-
CSI 2.8rCSI 17.5%PRS 72.2%
-
CSI 2.9rCSI 11.7%PRS 34.2%
-
CSI 2.9rCSI 4.4%PRS 35.1%
-
CSI 2.9rCSI 31.6%PRS 52.1%
-
CSI 2.9rCSI 3.5%PRS 53.5%
-
CSI 3.0rCSI 17.1%PRS 46.0%
-
CSI 3.0rCSI 2.6%PRS 42.9%
-
CSI 3.0rCSI 23.6%PRS 53.9%
-
CSI 3.0rCSI 4.6%PRS 39.1%
-
CSI 3.0rCSI 3.9%PRS 23.0%
-
CSI 3.2rCSI 4.5%PRS 32.5%
-
CSI 3.2rCSI 7.8%PRS 33.0%
-
CSI 3.2rCSI 9.2%PRS 55.8%
-
CSI 3.2rCSI 26.2%PRS 31.4%
-
CSI 3.3rCSI 76.7%PRS 90.7%
-
CSI 3.3rCSI 7.5%PRS 22.7%
-
CSI 3.4rCSI 44.5%PRS 70.0%
-
CSI 3.5rCSI 22.2%PRS 57.9%
-
CSI 3.5rCSI 6.3%PRS 50.1%
-
CSI 3.7rCSI 6.3%PRS 27.2%
-
CSI 3.7rCSI 5.1%PRS 63.4%
-
CSI 3.8rCSI 4.7%PRS 20.9%
-
CSI 3.8rCSI 9.2%PRS 21.5%
-
CSI 3.8rCSI 9.2%PRS 51.3%
-
CSI 3.8rCSI 4.4%PRS 45.6%
-
CSI 3.8rCSI 6.9%PRS 33.0%
-
CSI 3.9rCSI 2.6%PRS 43.2%
-
CSI 3.9rCSI 25.6%PRS 67.2%
-
CSI 3.9rCSI 8.7%PRS 25.5%
-
CSI 4.0rCSI 10.3%PRS 31.9%
-
CSI 4.1rCSI 8.4%PRS 32.0%
-
CSI 4.2rCSI 24.4%PRS 23.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
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Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2064189041
Symbol: MZT2A_HUMAN
Name: Mitotic-spindle organizing protein 2A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 20360068
Title: Systematic analysis of human protein complexes identifies chromosome segregation proteins.
PubMed ID: 20360068
Sequence Information:
- Length: 158
- Mass: 16221
- Checksum: B0B90630AE086B75
- Sequence:
MAAQGVGPGP GSAAPPGLEA ARQKLALRRK KVLSTEEMEL YELAQAAGGG IDPDVFKILV DLLKLNVAPL AVFQMLKSMC AGQRLASEPQ DPAAVSLPTS SVPETRGRDK GSAALGGVLA LAERSNHEGS SQRMPRQPSA TRLPKGGGPG KSPTQGST