MPZL1 | ENSG00000197965 | NCBI 9019

Details for: MPZL1

Gene ID: 9019

Symbol: MPZL1

Ensembl ID: ENSG00000197965

Description: myelin protein zero like 1

Associated with

Cell-cell signaling
(GO:0007267)
Cell surface
(GO:0009986)
Focal adhesion
(GO:0005925)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Structural molecule activity
(GO:0005198)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)

Other Information

Proteins

Myelin protein zero-like protein 1

Genular Protein ID: 781510641

Symbol: MPZL1_HUMAN

Name: Myelin protein zero-like protein 1

UniProtKB Accession Codes:

O95297 B2REB9 B2REC0 Q5R332 Q8IX11 Q9BWZ3 Q9NYK4 Q9UL20

Database IDs:

Citations:

PubMed ID: 9792637

Title: Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2.

PubMed ID: 9792637

DOI: 10.1074/jbc.273.45.29367

PubMed ID: 12075424

Title: Cloning of human myelin protein zero-like genes by bioinformatics strategy.

PubMed ID: 12075424

PubMed ID: 12684038

Title: Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs.

PubMed ID: 12684038

DOI: 10.1016/s0006-291x(03)00484-4

PubMed ID: 12410637

Title: Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration.

PubMed ID: 12410637

DOI: 10.1042/bj20020935

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10681522

Title: Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs.

PubMed ID: 10681522

DOI: 10.1074/jbc.275.8.5453

PubMed ID: 11751924

Title: Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling.

PubMed ID: 11751924

DOI: 10.1074/jbc.m111914200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30392906

Title: Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1.

PubMed ID: 30392906

DOI: 10.1016/j.bbrc.2018.10.161

Sequence Information:

Length: 269
Mass: 29082
Checksum: A1B299041EE59425
Sequence:

MAASAGAGAV IAAPDSRRWL WSVLAAALGL LTAGVSALEV YTPKEIFVAN GTQGKLTCKF 
KSTSTTGGLT SVSWSFQPEG ADTTVSFFHY SQGQVYLGNY PPFKDRISWA GDLDKKDASI 
NIENMQFIHN GTYICDVKNP PDIVVQPGHI RLYVVEKENL PVFPVWVVVG IVTAVVLGLT 
LLISMILAVL YRRKNSKRDY TGCSTSESLS PVKQAPRKSP SDTEGLVKSL PSGSHQGPVI 
YAQLDHSGGH HSDKINKSES VVYADIRKN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MPZL1

Associated with

Other Information

Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2. PubMed ID: 9792637

Cloning of human myelin protein zero-like genes by bioinformatics strategy. PubMed ID: 12075424

Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs. PubMed ID: 12684038

Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. PubMed ID: 12410637

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs. PubMed ID: 10681522

Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. PubMed ID: 11751924

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1. PubMed ID: 30392906