Details for: DDX1

Gene ID: 1653

Symbol: DDX1

Ensembl ID: ENSG00000079785

Description: DEAD-box helicase 1

Associated with

Other Information

Genular Protein ID: 1266991079

Symbol: DDX1_HUMAN

Name: ATP-dependent RNA helicase DDX1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7689221

Title: Amplification of a DEAD box protein gene in retinoblastoma cell lines.

PubMed ID: 7689221

DOI: 10.1073/pnas.90.16.7578

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11598190

Title: Association of human DEAD box protein DDX1 with a cleavage stimulation factor involved in 3'-end processing of pre-MRNA.

PubMed ID: 11598190

DOI: 10.1091/mbc.12.10.3046

PubMed ID: 12183465

Title: An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K.

PubMed ID: 12183465

DOI: 10.1074/jbc.m206981200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15567440

Title: A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev.

PubMed ID: 15567440

DOI: 10.1016/j.virol.2004.09.039

PubMed ID: 18335541

Title: MBNL1 associates with YB-1 in cytoplasmic stress granules.

PubMed ID: 18335541

DOI: 10.1002/jnr.21655

PubMed ID: 18710941

Title: A role for DEAD box 1 at DNA double-strand breaks.

PubMed ID: 18710941

DOI: 10.1128/mcb.01053-08

PubMed ID: 19058135

Title: The DEAD-box RNA helicase DDX1 interacts with RelA and enhances nuclear factor kappaB-mediated transcription.

PubMed ID: 19058135

DOI: 10.1002/jcb.22004

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20573827

Title: The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication.

PubMed ID: 20573827

DOI: 10.1128/jvi.00392-10

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21933836

Title: The X-chromosome-linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules.

PubMed ID: 21933836

DOI: 10.1093/hmg/ddr430

PubMed ID: 21589879

Title: A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.

PubMed ID: 21589879

DOI: 10.1371/journal.pone.0019810

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 21311021

Title: HSPC117 is the essential subunit of a human tRNA splicing ligase complex.

PubMed ID: 21311021

DOI: 10.1126/science.1197847

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24870230

Title: Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.

PubMed ID: 24870230

DOI: 10.1038/nature13284

PubMed ID: 24608264

Title: hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.

PubMed ID: 24608264

DOI: 10.1371/journal.pone.0090957

PubMed ID: 26030138

Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

PubMed ID: 26030138

DOI: 10.1371/journal.pone.0128558

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27105836

Title: Venezuelan equine encephalitis virus non-structural protein 3 (nsP3) interacts with RNA helicases DDX1 and DDX3 in infected cells.

PubMed ID: 27105836

DOI: 10.1016/j.antiviral.2016.04.008

PubMed ID: 28040436

Title: FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression.

PubMed ID: 28040436

DOI: 10.1016/j.biocel.2016.12.013

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 26323305

Title: Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.

PubMed ID: 26323305

DOI: 10.1107/s2053230x15013709

Sequence Information:

  • Length: 740
  • Mass: 82432
  • Checksum: C6D0179F83BD8C73
  • Sequence:
  • MAAFSEMGVM PEIAQAVEEM DWLLPTDIQA ESIPLILGGG DVLMAAETGS GKTGAFSIPV 
    IQIVYETLKD QQEGKKGKTT IKTGASVLNK WQMNPYDRGS AFAIGSDGLC CQSREVKEWH 
    GCRATKGLMK GKHYYEVSCH DQGLCRVGWS TMQASLDLGT DKFGFGFGGT GKKSHNKQFD 
    NYGEEFTMHD TIGCYLDIDK GHVKFSKNGK DLGLAFEIPP HMKNQALFPA CVLKNAELKF 
    NFGEEEFKFP PKDGFVALSK APDGYIVKSQ HSGNAQVTQT KFLPNAPKAL IVEPSRELAE 
    QTLNNIKQFK KYIDNPKLRE LLIIGGVAAR DQLSVLENGV DIVVGTPGRL DDLVSTGKLN 
    LSQVRFLVLD EADGLLSQGY SDFINRMHNQ IPQVTSDGKR LQVIVCSATL HSFDVKKLSE 
    KIMHFPTWVD LKGEDSVPDT VHHVVVPVNP KTDRLWERLG KSHIRTDDVH AKDNTRPGAN 
    SPEMWSEAIK ILKGEYAVRA IKEHKMDQAI IFCRTKIDCD NLEQYFIQQG GGPDKKGHQF 
    SCVCLHGDRK PHERKQNLER FKKGDVRFLI CTDVAARGID IHGVPYVINV TLPDEKQNYV 
    HRIGRVGRAE RMGLAISLVA TEKEKVWYHV CSSRGKGCYN TRLKEDGGCT IWYNEMQLLS 
    EIEEHLNCTI SQVEPDIKVP VDEFDGKVTY GQKRAAGGGS YKGHVDILAP TVQELAALEK 
    EAQTSFLHLG YLPNQLFRTF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.