Details for: RNF130
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 74.15rCSI 57.13%PRS 39.3
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CSI 64.67rCSI 59.38%PRS 47.69
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CSI 57.86rCSI 53.38%PRS 41.78
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CSI 47.81rCSI 80.25%PRS 26.58
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CSI 44.06rCSI 54.81%PRS 25.18
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CSI 43.88rCSI 52.42%PRS 26.51
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CSI 43.63rCSI 30.46%PRS 42.4
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CSI 42.97rCSI 75.89%PRS 25.65
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CSI 42.14rCSI 48.66%PRS 35.67
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CSI 41.83rCSI 67.28%PRS 28.6
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CSI 37.28rCSI 24.78%PRS 44.82
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CSI 36.47rCSI 32.37%PRS 40.01
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CSI 35.85rCSI 28.34%PRS 29.6
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CSI 35.39rCSI 66.8%PRS 50.3
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CSI 33.65rCSI 50.77%PRS 42.44
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CSI 31.64rCSI 43.95%PRS 40.37
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CSI 30.59rCSI 44.31%PRS 56.47
-
CSI 30.21rCSI 73.43%PRS 25.8
-
CSI 29.91rCSI 36.12%PRS 47.9
-
CSI 28.62rCSI 60.55%PRS 62.01
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CSI 28.23rCSI 88.21%PRS 27.68
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CSI 28.22rCSI 25.48%PRS 37.49
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CSI 27.69rCSI 23.12%PRS 62.8
-
CSI 27.57rCSI 40.87%PRS 84.66
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CSI 27.46rCSI 37.52%PRS 43.37
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CSI 26.02rCSI 33.39%PRS 38.79
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CSI 25.94rCSI 33.44%PRS 27.47
-
CSI 25.78rCSI 41.13%PRS 35.19
-
CSI 23.02rCSI 41.83%PRS 35.09
-
CSI 22.88rCSI 39.21%PRS 49.76
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CSI 22.74rCSI 50.05%PRS 28.26
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CSI 21.62rCSI 67.63%PRS 29.72
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CSI 21.11rCSI 26.29%PRS 51.73
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CSI 20.96rCSI 29.03%PRS 46.33
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CSI 20.85rCSI 78.8%PRS 27.46
-
CSI 20.68rCSI 61.13%PRS 32.53
-
CSI 20.41rCSI 37.13%PRS 70.73
-
CSI 20.1rCSI 33.1%PRS 46.03
-
CSI 19.86rCSI 26.02%PRS 53.6
-
CSI 19.83rCSI 58.54%PRS 44.82
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CSI 19.82rCSI 51.66%PRS 39.83
-
CSI 19.13rCSI 34.25%PRS 39.33
-
CSI 19.13rCSI 63.42%PRS 42.44
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CSI 18.57rCSI 66.84%PRS 25.53
-
CSI 18.41rCSI 23.1%PRS 49.98
-
CSI 17.75rCSI 47.27%PRS 34.02
-
CSI 17.17rCSI 20.9%PRS 48.07
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CSI 16.84rCSI 14.81%PRS 30.93
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CSI 16.58rCSI 24.37%PRS 37.42
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CSI 16.57rCSI 29.21%PRS 39.53
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CSI 16.34rCSI 16.81%PRS 57.98
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CSI 15.93rCSI 21.67%PRS 53.31
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CSI 15.82rCSI 21.03%PRS 45.1
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CSI 15.7rCSI 72.53%PRS 63.58
-
CSI 15.42rCSI 24.72%PRS 69.84
-
CSI 15.35rCSI 23.39%PRS 37.65
-
CSI 14.95rCSI 27.02%PRS 63.86
-
CSI 14.91rCSI 32.93%PRS 30.28
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CSI 14.73rCSI 14.92%PRS 81.22
-
CSI 14.38rCSI 17.72%PRS 66.01
-
CSI 14.19rCSI 36.04%PRS 37.43
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CSI 13.97rCSI 47.86%PRS 33.64
-
CSI 13.68rCSI 17.57%PRS 37.14
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CSI 13.66rCSI 21.98%PRS 32.37
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CSI 13.55rCSI 79.8%PRS 27.83
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CSI 12.91rCSI 26.2%PRS 24.89
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CSI 12.72rCSI 10.34%PRS 41.74
-
CSI 12.27rCSI 22.06%PRS 34.75
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CSI 12.15rCSI 26.35%PRS 31.88
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CSI 12.14rCSI 21.28%PRS 33.82
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CSI 12.11rCSI 17.38%PRS 32.98
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CSI 11.71rCSI 13.75%PRS 44.6
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CSI 11.58rCSI 23%PRS 40.51
-
CSI 11.39rCSI 25.99%PRS 34.97
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CSI 11.29rCSI 7.85%PRS 48.67
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CSI 11.28rCSI 12.35%PRS 44.54
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CSI 11.13rCSI 14.87%PRS 63.03
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CSI 11.07rCSI 11.05%PRS 35.43
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CSI 10.98rCSI 48.25%PRS 38.42
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CSI 10.9rCSI 12.6%PRS 31.69
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CSI 10.82rCSI 13.6%PRS 53.9
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CSI 10.82rCSI 10.07%PRS 40.66
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CSI 10.73rCSI 10.33%PRS 41.32
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CSI 10.59rCSI 64.09%PRS 65.85
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CSI 10.57rCSI 21.22%PRS 31.51
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CSI 10.57rCSI 9.15%PRS 44.37
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CSI 10.54rCSI 49.34%PRS 60.71
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CSI 10.51rCSI 7.78%PRS 35.12
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CSI 10.46rCSI 25.55%PRS 37.39
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CSI 10.4rCSI 76.46%PRS 29.82
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CSI 10.37rCSI 22.04%PRS 45.86
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CSI 10.34rCSI 13.16%PRS 45.71
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CSI 10.31rCSI 13.78%PRS 48.83
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CSI 10.22rCSI 41.12%PRS 52.38
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CSI 10.16rCSI 38.33%PRS 35.69
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CSI 10.12rCSI 26.72%PRS 47.86
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CSI 9.96rCSI 8.25%PRS 41.56
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CSI 9.88rCSI 7.66%PRS 41
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CSI 9.71rCSI 18.19%PRS 31.51
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CSI 9.59rCSI 63.64%PRS 39.94
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CSI 0.1rCSI 1.1%PRS 64.1%
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CSI 0.2rCSI 5.8%PRS 65.8%
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CSI 0.2rCSI 2.3%PRS 61.7%
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CSI 0.4rCSI 2.4%PRS 59.6%
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CSI 0.4rCSI 1.4%PRS 60.6%
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CSI 0.4rCSI 1.6%PRS 57.5%
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CSI 0.4rCSI 0.6%PRS 49.8%
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CSI 0.6rCSI 3.1%PRS 51.1%
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CSI 0.7rCSI 3.8%PRS 76.6%
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CSI 0.7rCSI 4.7%PRS 74.4%
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CSI 0.7rCSI 2.1%PRS 55.5%
-
CSI 0.7rCSI 4.0%PRS 56.6%
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CSI 0.8rCSI 2.2%PRS 56.2%
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CSI 0.8rCSI 3.2%PRS 62.5%
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CSI 1.0rCSI 10.6%PRS 57.7%
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CSI 1.0rCSI 2.2%PRS 60.7%
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CSI 1.1rCSI 2.0%PRS 56.6%
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CSI 1.1rCSI 4.4%PRS 43.9%
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CSI 1.2rCSI 3.9%PRS 40.3%
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CSI 1.2rCSI 1.9%PRS 38.8%
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CSI 1.2rCSI 5.4%PRS 39.4%
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CSI 1.2rCSI 9.3%PRS 61.0%
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CSI 1.3rCSI 7.4%PRS 51.8%
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CSI 1.3rCSI 1.7%PRS 45.4%
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CSI 1.3rCSI 4.2%PRS 48.8%
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CSI 1.3rCSI 14.2%PRS 42.8%
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CSI 1.4rCSI 17.9%PRS 74.5%
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CSI 1.4rCSI 15.0%PRS 73.5%
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CSI 1.4rCSI 3.9%PRS 41.9%
-
CSI 1.4rCSI 7.1%PRS 52.0%
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CSI 1.5rCSI 12.2%PRS 37.5%
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CSI 1.5rCSI 9.2%PRS 34.0%
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CSI 1.5rCSI 1.1%PRS 52.4%
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CSI 1.5rCSI 5.9%PRS 59.7%
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CSI 1.6rCSI 14.5%PRS 30.2%
-
CSI 1.7rCSI 4.9%PRS 72.4%
-
CSI 1.7rCSI 7.4%PRS 60.2%
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CSI 1.7rCSI 6.9%PRS 52.9%
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CSI 1.8rCSI 2.8%PRS 41.8%
-
CSI 1.8rCSI 1.9%PRS 43.2%
-
CSI 1.9rCSI 18.0%PRS 60.4%
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CSI 2.0rCSI 21.9%PRS 67.7%
-
CSI 2.0rCSI 10.5%PRS 39.2%
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CSI 2.0rCSI 23.2%PRS 36.2%
-
CSI 2.0rCSI 5.4%PRS 63.7%
-
CSI 2.1rCSI 4.3%PRS 63.1%
-
CSI 2.1rCSI 13.2%PRS 27.4%
-
CSI 2.1rCSI 11.5%PRS 55.9%
-
CSI 2.1rCSI 13.2%PRS 63.6%
-
CSI 2.2rCSI 3.0%PRS 50.8%
-
CSI 2.2rCSI 3.2%PRS 50.7%
-
CSI 2.3rCSI 3.3%PRS 54.4%
-
CSI 2.3rCSI 6.1%PRS 49.6%
-
CSI 2.3rCSI 12.0%PRS 55.9%
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CSI 2.3rCSI 2.9%PRS 36.9%
-
CSI 2.3rCSI 13.1%PRS 73.5%
-
CSI 2.4rCSI 2.4%PRS 46.4%
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CSI 2.4rCSI 12.8%PRS 50.5%
-
CSI 2.4rCSI 13.9%PRS 73.0%
-
CSI 2.5rCSI 58.2%PRS 63.6%
-
CSI 2.7rCSI 15.3%PRS 51.6%
-
CSI 2.7rCSI 4.3%PRS 44.1%
-
CSI 2.8rCSI 6.7%PRS 51.2%
-
CSI 2.8rCSI 6.3%PRS 38.1%
-
CSI 2.8rCSI 21.4%PRS 37.4%
-
CSI 2.9rCSI 7.4%PRS 44.1%
-
CSI 2.9rCSI 13.0%PRS 28.3%
-
CSI 2.9rCSI 7.0%PRS 57.3%
-
CSI 2.9rCSI 7.0%PRS 51.7%
-
CSI 3.1rCSI 3.5%PRS 63.4%
-
CSI 3.1rCSI 74.6%PRS 26.9%
-
CSI 3.1rCSI 74.7%PRS 26.0%
-
CSI 3.2rCSI 13.5%PRS 39.0%
-
CSI 3.2rCSI 13.2%PRS 42.5%
-
CSI 3.2rCSI 65.0%PRS 35.4%
-
CSI 3.3rCSI 15.4%PRS 39.3%
-
CSI 3.3rCSI 66.5%PRS 34.2%
-
CSI 3.3rCSI 9.5%PRS 43.3%
-
CSI 3.3rCSI 4.1%PRS 43.4%
-
CSI 3.3rCSI 3.0%PRS 61.0%
-
CSI 3.3rCSI 2.2%PRS 50.2%
-
CSI 3.4rCSI 14.4%PRS 64.3%
-
CSI 3.5rCSI 17.5%PRS 78.0%
-
CSI 3.5rCSI 15.1%PRS 56.6%
-
CSI 3.5rCSI 18.6%PRS 79.5%
-
CSI 3.5rCSI 5.0%PRS 38.1%
-
CSI 3.5rCSI 20.9%PRS 39.4%
-
CSI 3.6rCSI 8.5%PRS 31.1%
-
CSI 3.6rCSI 5.3%PRS 51.4%
-
CSI 3.6rCSI 51.0%PRS 34.0%
-
CSI 3.6rCSI 5.5%PRS 58.0%
-
CSI 3.7rCSI 26.3%PRS 37.3%
-
CSI 3.7rCSI 5.7%PRS 56.9%
-
CSI 3.7rCSI 12.1%PRS 30.6%
-
CSI 3.8rCSI 9.7%PRS 48.7%
-
CSI 3.8rCSI 5.8%PRS 41.3%
-
CSI 3.8rCSI 10.0%PRS 49.7%
-
CSI 3.8rCSI 33.1%PRS 43.4%
-
CSI 3.9rCSI 61.4%PRS 44.0%
-
CSI 3.9rCSI 9.4%PRS 58.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2616940261
Symbol: GOLI_HUMAN
Name: E3 ubiquitin-protein ligase RNF130
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 13679316
Title: Goliath, a ring-H2 mitochondrial protein, regulated by luteinizing hormone/human chorionic gonadotropin in rat Leydig cells.
PubMed ID: 13679316
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16549277
Title: h-Goliath, paralog of GRAIL, is a new E3 ligase protein, expressed in human leukocytes.
PubMed ID: 16549277
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
Sequence Information:
- Length: 419
- Mass: 46405
- Checksum: 74E8D987334F3B8E
- Sequence:
MSCAGRAGPA RLAALALLTC SLWPARADNA SQEYYTALIN VTVQEPGRGA PLTFRIDRGR YGLDSPKAEV RGQVLAPLPL HGVADHLGCD PQTRFFVPPN IKQWIALLQR GNCTFKEKIS RAAFHNAVAV VIYNNKSKEE PVTMTHPGTG DIIAVMITEL RGKDILSYLE KNISVQMTIA VGTRMPPKNF SRGSLVFVSI SFIVLMIISS AWLIFYFIQK IRYTNARDRN QRRLGDAAKK AISKLTTRTV KKGDKETDPD FDHCAVCIES YKQNDVVRIL PCKHVFHKSC VDPWLSEHCT CPMCKLNILK ALGIVPNLPC TDNVAFDMER LTRTQAVNRR SALGDLAGDN SLGLEPLRTS GISPLPQDGE LTPRTGEINI AVTKEWFIIA SFGLLSALTL CYMIIRATAS LNANEVEWF
Genular Protein ID: 724104412
Symbol: Q2HIY3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 276
- Mass: 30810
- Checksum: 6E9F599E2315EC90
- Sequence:
MTHPGTGDII AVMITELRGK DILSYLEKNI SVQMTIAVGT RMPPKNFSRG SLVFVSISFI VLMIISSAWL IFYFIQKIRY TNARDRNQRR LGDAAKKAIS KLTTRTVKKG DKETDPDFDH CAVCIESYKQ NDVVRILPCK HVFHKSCVDP WLSEHCTCPM CKLNILKALG IVPNLPCTDN VAFDMERLTR TQAVNRRSAL GDLAGDNSLG LEPLRTSGIS PLPQDGELTP RTGEINIAVT KEWFIIASFG LLSALTLCYM IIRATASLNA NEVEWF