Details for: KRTCAP2
Gene ID: 200185
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: KRTCAP2
Ensembl ID: ENSG00000163463
Description: keratinocyte associated protein 2
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 86.09rCSI 67.73%PRS 30.55
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CSI 68.54rCSI 60.27%PRS 18.47
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CSI 56.56rCSI 55.63%PRS 27.03
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CSI 53.76rCSI 46.55%PRS 28.35
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CSI 51.06rCSI 52.27%PRS 44.11
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CSI 45.68rCSI 66.83%PRS 26.78
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CSI 37.83rCSI 39.63%PRS 26.8
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CSI 36.34rCSI 34.98%PRS 26.12
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CSI 36.28rCSI 44.88%PRS 22.26
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CSI 34.4rCSI 31.07%PRS 23.04
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CSI 34rCSI 23.74%PRS 26.87
-
CSI 33.41rCSI 39.23%PRS 28.87
-
CSI 33.26rCSI 32.07%PRS 18.67
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CSI 32.5rCSI 21.6%PRS 29.81
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CSI 30.83rCSI 100%PRS 29.75
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CSI 29.75rCSI 24.06%PRS 25.45
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CSI 29.4rCSI 38.53%PRS 71.4
-
CSI 28.93rCSI 38.7%PRS 66.77
-
CSI 28.62rCSI 29.98%PRS 23.58
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CSI 26.73rCSI 32.02%PRS 42.56
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CSI 26.71rCSI 38.52%PRS 34.71
-
CSI 26.43rCSI 57.71%PRS 46.05
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CSI 26.24rCSI 26.19%PRS 21.64
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CSI 25.18rCSI 22.35%PRS 25.53
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CSI 24.01rCSI 17.84%PRS 36.62
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CSI 23.49rCSI 52.72%PRS 46.45
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CSI 23.48rCSI 21.56%PRS 30.04
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CSI 23.47rCSI 45.88%PRS 86.09
-
CSI 23.07rCSI 33.79%PRS 28.17
-
CSI 22.78rCSI 29.22%PRS 29.08
-
CSI 21.96rCSI 21.68%PRS 69.49
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CSI 21.92rCSI 25.42%PRS 35.84
-
CSI 21.9rCSI 26.14%PRS 42.83
-
CSI 21.59rCSI 17.55%PRS 26.36
-
CSI 20.76rCSI 21.7%PRS 26.06
-
CSI 20.71rCSI 49.23%PRS 36.85
-
CSI 19.93rCSI 16.53%PRS 23.99
-
CSI 18.86rCSI 28.81%PRS 25.36
-
CSI 18.47rCSI 28.25%PRS 40.03
-
CSI 18.44rCSI 40.81%PRS 23.31
-
CSI 18.1rCSI 41.07%PRS 32.42
-
CSI 17.94rCSI 30.65%PRS 49.19
-
CSI 17.9rCSI 30.67%PRS 33.82
-
CSI 17.88rCSI 34.09%PRS 39.22
-
CSI 17.67rCSI 25.47%PRS 38.67
-
CSI 17.62rCSI 21.71%PRS 60.45
-
CSI 17.6rCSI 16.03%PRS 37.97
-
CSI 17.41rCSI 21.85%PRS 32.61
-
CSI 17.13rCSI 17.87%PRS 25.86
-
CSI 16.94rCSI 18.16%PRS 23.26
-
CSI 16.89rCSI 48.02%PRS 27.55
-
CSI 16.81rCSI 12.95%PRS 23.69
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CSI 16.51rCSI 15.37%PRS 25.23
-
CSI 16.27rCSI 37.13%PRS 21.56
-
CSI 15.77rCSI 27.8%PRS 32.32
-
CSI 15.72rCSI 34.6%PRS 28.85
-
CSI 15.61rCSI 64.31%PRS 54.14
-
CSI 15.53rCSI 36.45%PRS 35.06
-
CSI 14.82rCSI 18.04%PRS 31.24
-
CSI 14.54rCSI 10.21%PRS 53.44
-
CSI 14.51rCSI 57.76%PRS 41.24
-
CSI 14.32rCSI 9.96%PRS 35.36
-
CSI 13.9rCSI 30.01%PRS 69.09
-
CSI 13.89rCSI 46.97%PRS 38.12
-
CSI 13.62rCSI 11.42%PRS 29.81
-
CSI 13.58rCSI 16.91%PRS 34.63
-
CSI 13.56rCSI 27.23%PRS 18.71
-
CSI 13.56rCSI 12.53%PRS 44.1
-
CSI 13.55rCSI 20.04%PRS 28.7
-
CSI 13.49rCSI 26.24%PRS 25.96
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CSI 13.43rCSI 17.85%PRS 27.68
-
CSI 13.31rCSI 18.19%PRS 37.07
-
CSI 13.08rCSI 37.86%PRS 28.18
-
CSI 12.97rCSI 16.13%PRS 26.96
-
CSI 12.72rCSI 20.32%PRS 27.61
-
CSI 12.65rCSI 10.22%PRS 37
-
CSI 12.52rCSI 10.53%PRS 39.44
-
CSI 12.51rCSI 19.12%PRS 32.57
-
CSI 12.49rCSI 9.87%PRS 17.37
-
CSI 12.43rCSI 10.81%PRS 31.82
-
CSI 12.18rCSI 56.77%PRS 50.76
-
CSI 12.15rCSI 9.24%PRS 33.42
-
CSI 12.08rCSI 16.72%PRS 33.6
-
CSI 11.94rCSI 19.15%PRS 59.22
-
CSI 11.94rCSI 8.94%PRS 38.9
-
CSI 11.74rCSI 16.64%PRS 23.36
-
CSI 11.74rCSI 11.96%PRS 35.69
-
CSI 11.64rCSI 9.64%PRS 25.67
-
CSI 11.4rCSI 14.58%PRS 69.37
-
CSI 11.35rCSI 49.05%PRS 43.46
-
CSI 11.24rCSI 39.42%PRS 41.98
-
CSI 11.23rCSI 16.64%PRS 83.03
-
CSI 11.18rCSI 8.03%PRS 34.66
-
CSI 11.17rCSI 7.52%PRS 31.39
-
CSI 11.03rCSI 11.17%PRS 77
-
CSI 10.68rCSI 14.83%PRS 25.5
-
CSI 10.64rCSI 8.88%PRS 56.13
-
CSI 10.64rCSI 10.45%PRS 59.4
-
CSI 10.56rCSI 17.39%PRS 29.67
-
CSI 10.48rCSI 51.64%PRS 33.83
-
CSI 0.1rCSI 0.3%PRS 18.1%
-
CSI 0.2rCSI 3.6%PRS 68.5%
-
CSI 0.3rCSI 5.7%PRS 80.9%
-
CSI 0.5rCSI 3.4%PRS 44.4%
-
CSI 0.5rCSI 2.7%PRS 62.5%
-
CSI 0.5rCSI 5.8%PRS 71.8%
-
CSI 0.6rCSI 4.4%PRS 45.9%
-
CSI 0.7rCSI 1.9%PRS 19.7%
-
CSI 0.7rCSI 16.9%PRS 58.8%
-
CSI 0.7rCSI 1.1%PRS 25.9%
-
CSI 0.8rCSI 2.2%PRS 38.4%
-
CSI 0.8rCSI 10.4%PRS 63.7%
-
CSI 0.8rCSI 20.5%PRS 84.0%
-
CSI 0.9rCSI 3.3%PRS 41.0%
-
CSI 0.9rCSI 21.0%PRS 45.6%
-
CSI 0.9rCSI 1.4%PRS 38.8%
-
CSI 1.0rCSI 6.3%PRS 64.3%
-
CSI 1.0rCSI 9.6%PRS 73.6%
-
CSI 1.1rCSI 2.8%PRS 32.5%
-
CSI 1.1rCSI 2.8%PRS 21.0%
-
CSI 1.1rCSI 1.7%PRS 21.2%
-
CSI 1.1rCSI 11.7%PRS 42.7%
-
CSI 1.1rCSI 5.5%PRS 33.3%
-
CSI 1.1rCSI 24.7%PRS 71.7%
-
CSI 1.1rCSI 22.1%PRS 58.7%
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CSI 1.1rCSI 2.0%PRS 15.0%
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CSI 1.2rCSI 3.3%PRS 43.8%
-
CSI 1.2rCSI 5.7%PRS 48.8%
-
CSI 1.3rCSI 34.8%PRS 73.5%
-
CSI 1.3rCSI 2.9%PRS 33.3%
-
CSI 1.4rCSI 6.2%PRS 67.5%
-
CSI 1.4rCSI 41.2%PRS 50.5%
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CSI 1.4rCSI 13.6%PRS 56.6%
-
CSI 1.4rCSI 6.4%PRS 63.4%
-
CSI 1.4rCSI 4.1%PRS 48.5%
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CSI 1.4rCSI 34.4%PRS 61.7%
-
CSI 1.4rCSI 5.1%PRS 65.6%
-
CSI 1.5rCSI 1.9%PRS 45.8%
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CSI 1.5rCSI 1.4%PRS 48.4%
-
CSI 1.5rCSI 3.9%PRS 36.7%
-
CSI 1.6rCSI 2.3%PRS 19.7%
-
CSI 1.6rCSI 4.2%PRS 55.9%
-
CSI 1.7rCSI 4.4%PRS 31.3%
-
CSI 1.8rCSI 2.1%PRS 24.5%
-
CSI 1.8rCSI 6.5%PRS 42.1%
-
CSI 1.8rCSI 4.8%PRS 25.1%
-
CSI 1.9rCSI 10.7%PRS 36.7%
-
CSI 1.9rCSI 28.5%PRS 58.9%
-
CSI 1.9rCSI 4.5%PRS 53.7%
-
CSI 2.0rCSI 3.9%PRS 54.1%
-
CSI 2.1rCSI 6.6%PRS 34.3%
-
CSI 2.2rCSI 11.7%PRS 41.9%
-
CSI 2.2rCSI 34.2%PRS 55.3%
-
CSI 2.3rCSI 5.5%PRS 28.1%
-
CSI 2.4rCSI 25.3%PRS 30.9%
-
CSI 2.4rCSI 3.5%PRS 28.0%
-
CSI 2.5rCSI 7.0%PRS 40.5%
-
CSI 2.5rCSI 20.1%PRS 68.9%
-
CSI 2.6rCSI 6.4%PRS 59.6%
-
CSI 2.6rCSI 5.6%PRS 37.4%
-
CSI 2.6rCSI 15.1%PRS 36.2%
-
CSI 2.7rCSI 3.4%PRS 24.3%
-
CSI 2.9rCSI 11.0%PRS 45.6%
-
CSI 3.0rCSI 13.8%PRS 55.4%
-
CSI 3.1rCSI 7.4%PRS 42.5%
-
CSI 3.1rCSI 6.2%PRS 26.1%
-
CSI 3.2rCSI 4.6%PRS 37.8%
-
CSI 3.2rCSI 17.0%PRS 38.9%
-
CSI 3.3rCSI 5.9%PRS 55.1%
-
CSI 3.3rCSI 14.5%PRS 24.5%
-
CSI 3.4rCSI 6.1%PRS 38.1%
-
CSI 3.4rCSI 8.6%PRS 19.3%
-
CSI 3.4rCSI 3.9%PRS 39.6%
-
CSI 3.5rCSI 15.2%PRS 41.6%
-
CSI 3.5rCSI 18.3%PRS 47.4%
-
CSI 3.6rCSI 20.4%PRS 64.5%
-
CSI 3.6rCSI 6.8%PRS 61.3%
-
CSI 3.7rCSI 4.3%PRS 18.7%
-
CSI 3.8rCSI 9.7%PRS 30.9%
-
CSI 3.8rCSI 7.2%PRS 46.6%
-
CSI 3.8rCSI 5.9%PRS 23.7%
-
CSI 3.9rCSI 5.9%PRS 28.8%
-
CSI 3.9rCSI 5.5%PRS 34.8%
-
CSI 3.9rCSI 8.3%PRS 39.1%
-
CSI 4.1rCSI 25.4%PRS 65.3%
-
CSI 4.1rCSI 15.7%PRS 23.5%
-
CSI 4.2rCSI 11.8%PRS 31.3%
-
CSI 4.3rCSI 23.2%PRS 68.1%
-
CSI 4.3rCSI 15.4%PRS 39.5%
-
CSI 4.4rCSI 7.5%PRS 46.2%
-
CSI 4.5rCSI 10.8%PRS 36.1%
-
CSI 4.6rCSI 11.6%PRS 24.7%
-
CSI 4.6rCSI 3.6%PRS 44.0%
-
CSI 4.7rCSI 12.0%PRS 23.3%
-
CSI 4.7rCSI 25.8%PRS 52.4%
-
CSI 4.8rCSI 19.0%PRS 49.1%
-
CSI 4.9rCSI 8.7%PRS 40.2%
-
CSI 4.9rCSI 4.3%PRS 29.1%
-
CSI 4.9rCSI 31.6%PRS 49.4%
-
CSI 4.9rCSI 18.4%PRS 21.2%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2178979339
Symbol: KTAP2_HUMAN
Name: Keratinocyte-associated protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12752121
Title: Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
PubMed ID: 12752121
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21768116
Title: DC2 and keratinocyte-associated protein 2 (KCP2), subunits of the oligosaccharyltransferase complex, are regulators of the gamma-secretase-directed processing of amyloid precursor protein (APP).
PubMed ID: 21768116
PubMed ID: 22266900
Title: Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase.
PubMed ID: 22266900
DOI: 10.1242/jcs.094599
PubMed ID: 22467853
Title: The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.
PubMed ID: 22467853
DOI: 10.1242/jcs.103952
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 136
- Mass: 14679
- Checksum: 090926F115D7532B
- Sequence:
MVVGTGTSLA LSSLLSLLLF AGMQMYSRQL ASTEWLTIQG GLLGSGLFVF SLTAFNNLEN LVFGKGFQAK IFPEILLCLL LALFASGLIH RVCVTTCFIF SMVGLYYINK ISSTLYQAAA PVLTPAKVTG KSKKRN