DRAP1 | ENSG00000175550 | NCBI 10589

Details for: DRAP1

Gene ID: 10589

Symbol: DRAP1

Ensembl ID: ENSG00000175550

Description: DR1 associated protein 1

Associated with

Developmental biology
(R-HSA-1266738)
Signaling by activin
(R-HSA-1502540)
Signaling by nodal
(R-HSA-1181150)
Signaling by tgfb family members
(R-HSA-9006936)
Signal transduction
(R-HSA-162582)
Core promoter sequence-specific dna binding
(GO:0001046)
Dna binding
(GO:0003677)
Identical protein binding
(GO:0042802)
Negative cofactor 2 complex
(GO:0017054)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Rna polymerase ii general transcription initiation factor activity
(GO:0016251)
Rna polymerase ii general transcription initiation factor binding
(GO:0001091)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Tbp-class protein binding
(GO:0017025)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

Dr1-associated corepressor

Genular Protein ID: 361570448

Symbol: NC2A_HUMAN

Name: Dr1-associated corepressor

UniProtKB Accession Codes:

Q14919 Q13448

Database IDs:

Citations:

PubMed ID: 8670811

Title: A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

PubMed ID: 8670811

DOI: 10.1002/j.1460-2075.1996.tb00673.x

PubMed ID: 8608938

Title: Requirement of a corepressor for Dr1-mediated repression of transcription.

PubMed ID: 8608938

DOI: 10.1101/gad.10.8.1033

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15509807

Title: NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein.

PubMed ID: 15509807

DOI: 10.1128/mcb.24.22.10072-10082.2004

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 11461703

Title: Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.

PubMed ID: 11461703

DOI: 10.1016/s0092-8674(01)00417-2

Sequence Information:

Length: 205
Mass: 22350
Checksum: 6154C43C6B8DC877
Sequence:

MPSKKKKYNA RFPPARIKKI MQTDEEIGKV AAAVPVIISR ALELFLESLL KKACQVTQSR 
NAKTMTTSHL KQCIELEQQF DFLKDLVASV PDMQGDGEDN HMDGDKGARR GRKPGSGGRK 
NGGMGTKSKD KKLSGTDSEQ EDESEDTDTD GEEETSQPPP QASHPSAHFQ SPPTPFLPFA 
STLPLPPAPP GPSAPDEEDE EDYDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: DRAP1

Associated with

Other Information

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains. PubMed ID: 8670811

Requirement of a corepressor for Dr1-mediated repression of transcription. PubMed ID: 8608938

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. PubMed ID: 15509807

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. PubMed ID: 11461703