Details for: RPAIN
Gene ID: 84268
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: RPAIN
Ensembl ID: ENSG00000129197
Description: RPA interacting protein
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 40.16rCSI 54.72%PRS 27.54
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CSI 23.39rCSI 21.12%PRS 29.24
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CSI 20.09rCSI 21.04%PRS 29.84
-
CSI 17.26rCSI 30.43%PRS 39.73
-
CSI 15.9rCSI 51.03%PRS 40.82
-
CSI 12.33rCSI 12.92%PRS 33.86
-
CSI 12.33rCSI 18.2%PRS 47.45
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CSI 11.99rCSI 19.34%PRS 42.96
-
CSI 11.7rCSI 15.01%PRS 30.47
-
CSI 11.46rCSI 25.24%PRS 45.66
-
CSI 11.2rCSI 18.79%PRS 20.08
-
CSI 10.89rCSI 28.15%PRS 29.3
-
CSI 10.86rCSI 9.55%PRS 23.64
-
CSI 10.17rCSI 30.18%PRS 42.15
-
CSI 10.07rCSI 20.7%PRS 29.58
-
CSI 9.98rCSI 38.57%PRS 52.6
-
CSI 9.63rCSI 41.79%PRS 48.32
-
CSI 9.52rCSI 14.51%PRS 29.61
-
CSI 9.17rCSI 71.88%PRS 51.47
-
CSI 8.86rCSI 26.14%PRS 36.57
-
CSI 8.41rCSI 15.9%PRS 56.62
-
CSI 7.89rCSI 86.36%PRS 49.62
-
CSI 7.27rCSI 16.09%PRS 29.61
-
CSI 7.13rCSI 23.88%PRS 23.78
-
CSI 7.03rCSI 18.55%PRS 37.66
-
CSI 6.83rCSI 17.99%PRS 54.89
-
CSI 6.77rCSI 19.42%PRS 46.65
-
CSI 6.76rCSI 5.08%PRS 34.28
-
CSI 6.58rCSI 41.08%PRS 26.13
-
CSI 6.23rCSI 6.12%PRS 46.11
-
CSI 5.91rCSI 13.24%PRS 20.66
-
CSI 5.72rCSI 6.61%PRS 27.87
-
CSI 5.56rCSI 20.13%PRS 50.01
-
CSI 5.53rCSI 7.56%PRS 35.73
-
CSI 5.4rCSI 8.68%PRS 21.82
-
CSI 5.32rCSI 7.27%PRS 34.66
-
CSI 5.32rCSI 8.49%PRS 34.77
-
CSI 5.14rCSI 10%PRS 33.13
-
CSI 5.1rCSI 8.74%PRS 40.92
-
CSI 5.1rCSI 6.57%PRS 20.8
-
CSI 4.83rCSI 4.2%PRS 39.52
-
CSI 4.49rCSI 6.97%PRS 42.81
-
CSI 4.48rCSI 23.11%PRS 55.07
-
CSI 4.4rCSI 3.06%PRS 38.44
-
CSI 4.38rCSI 9.94%PRS 38.63
-
CSI 4.25rCSI 4.18%PRS 34.12
-
CSI 4.22rCSI 5.37%PRS 36.49
-
CSI 4.2rCSI 3.62%PRS 42.41
-
CSI 4.15rCSI 26.7%PRS 55.19
-
CSI 4.06rCSI 10.27%PRS 38.86
-
CSI 4.06rCSI 5.64%PRS 32.14
-
CSI 4.06rCSI 3.09%PRS 41.4
-
CSI 4.05rCSI 2.69%PRS 36.29
-
CSI 4.03rCSI 5.58%PRS 39.07
-
CSI 3.97rCSI 21.4%PRS 47.36
-
CSI 3.93rCSI 3.48%PRS 31.64
-
CSI 3.9rCSI 6.84%PRS 25.63
-
CSI 3.9rCSI 3.15%PRS 32.1
-
CSI 3.88rCSI 14.64%PRS 31.88
-
CSI 3.82rCSI 4.42%PRS 24.11
-
CSI 3.73rCSI 4.98%PRS 53.93
-
CSI 3.7rCSI 7.38%PRS 49.27
-
CSI 3.68rCSI 17.25%PRS 60.96
-
CSI 3.63rCSI 53.7%PRS 57.89
-
CSI 3.59rCSI 2.88%PRS 52.16
-
CSI 3.59rCSI 2.58%PRS 42.8
-
CSI 3.56rCSI 5.76%PRS 31.39
-
CSI 3.44rCSI 7.68%PRS 37.13
-
CSI 3.29rCSI 2.55%PRS 31.44
-
CSI 3.21rCSI 2.38%PRS 44.11
-
CSI 3.17rCSI 3.57%PRS 47.17
-
CSI 3.17rCSI 2.93%PRS 51.73
-
CSI 3.09rCSI 5.89%PRS 47.63
-
CSI 2.98rCSI 2.21%PRS 27.43
-
CSI 2.92rCSI 7.41%PRS 30.27
-
CSI 2.89rCSI 11.48%PRS 48.21
-
CSI 2.85rCSI 5.08%PRS 47.66
-
CSI 2.84rCSI 1.91%PRS 39.84
-
CSI 2.81rCSI 3.86%PRS 52.94
-
CSI 2.8rCSI 4.31%PRS 37.95
-
CSI 2.78rCSI 14.95%PRS 48.53
-
CSI 2.77rCSI 2.67%PRS 24.44
-
CSI 2.76rCSI 5.88%PRS 40.09
-
CSI 2.72rCSI 1.61%PRS 44.11
-
CSI 2.71rCSI 3.37%PRS 18.94
-
CSI 2.69rCSI 6.55%PRS 19.57
-
CSI 2.61rCSI 2.43%PRS 31.86
-
CSI 2.59rCSI 3.69%PRS 34.65
-
CSI 2.53rCSI 5.19%PRS 55.3
-
CSI 2.52rCSI 3.69%PRS 33.92
-
CSI 2.5rCSI 3.86%PRS 30.21
-
CSI 2.49rCSI 3.93%PRS 32.44
-
CSI 2.42rCSI 4.85%PRS 24.15
-
CSI 2.41rCSI 2.03%PRS 47.59
-
CSI 2.38rCSI 1.87%PRS 37.65
-
CSI 2.37rCSI 3.69%PRS 59.44
-
CSI 2.35rCSI 3.85%PRS 25.05
-
CSI 2.33rCSI 7.28%PRS 21.04
-
CSI 2.31rCSI 1.88%PRS 32.84
-
CSI 2.26rCSI 2.89%PRS 36.45
-
CSI 0.1rCSI 0.8%PRS 44.0%
-
CSI 0.2rCSI 5.1%PRS 54.4%
-
CSI 0.3rCSI 5.4%PRS 86.4%
-
CSI 0.3rCSI 1.1%PRS 70.7%
-
CSI 0.3rCSI 7.4%PRS 20.2%
-
CSI 0.3rCSI 1.5%PRS 57.4%
-
CSI 0.3rCSI 3.5%PRS 53.3%
-
CSI 0.4rCSI 1.8%PRS 71.6%
-
CSI 0.4rCSI 2.4%PRS 43.6%
-
CSI 0.4rCSI 1.1%PRS 24.9%
-
CSI 0.5rCSI 0.7%PRS 24.9%
-
CSI 0.5rCSI 1.1%PRS 47.6%
-
CSI 0.5rCSI 0.6%PRS 50.8%
-
CSI 0.5rCSI 0.7%PRS 41.7%
-
CSI 0.5rCSI 2.1%PRS 30.8%
-
CSI 0.5rCSI 4.6%PRS 56.8%
-
CSI 0.5rCSI 0.7%PRS 34.0%
-
CSI 0.5rCSI 4.0%PRS 52.3%
-
CSI 0.5rCSI 3.2%PRS 21.2%
-
CSI 0.5rCSI 13.0%PRS 19.4%
-
CSI 0.6rCSI 1.0%PRS 40.2%
-
CSI 0.6rCSI 0.9%PRS 37.6%
-
CSI 0.6rCSI 3.0%PRS 41.9%
-
CSI 0.6rCSI 0.6%PRS 37.8%
-
CSI 0.6rCSI 1.7%PRS 47.9%
-
CSI 0.6rCSI 2.2%PRS 46.3%
-
CSI 0.6rCSI 1.2%PRS 24.1%
-
CSI 0.6rCSI 2.7%PRS 49.8%
-
CSI 0.6rCSI 1.4%PRS 23.2%
-
CSI 0.6rCSI 2.8%PRS 51.8%
-
CSI 0.6rCSI 2.5%PRS 50.2%
-
CSI 0.7rCSI 4.0%PRS 58.3%
-
CSI 0.7rCSI 1.8%PRS 40.3%
-
CSI 0.7rCSI 1.4%PRS 54.3%
-
CSI 0.7rCSI 1.0%PRS 60.7%
-
CSI 0.7rCSI 10.1%PRS 26.5%
-
CSI 0.7rCSI 2.6%PRS 19.1%
-
CSI 0.7rCSI 4.5%PRS 70.6%
-
CSI 0.7rCSI 1.2%PRS 27.0%
-
CSI 0.7rCSI 1.6%PRS 53.0%
-
CSI 0.8rCSI 0.9%PRS 40.3%
-
CSI 0.8rCSI 4.1%PRS 57.9%
-
CSI 0.8rCSI 4.0%PRS 47.9%
-
CSI 0.8rCSI 3.4%PRS 27.9%
-
CSI 0.8rCSI 7.4%PRS 77.8%
-
CSI 0.8rCSI 1.4%PRS 19.5%
-
CSI 0.8rCSI 2.7%PRS 66.1%
-
CSI 0.8rCSI 2.0%PRS 44.1%
-
CSI 0.8rCSI 2.0%PRS 43.1%
-
CSI 0.9rCSI 1.2%PRS 43.4%
-
CSI 0.9rCSI 1.2%PRS 34.1%
-
CSI 1.0rCSI 1.5%PRS 47.9%
-
CSI 1.0rCSI 1.4%PRS 39.9%
-
CSI 1.0rCSI 2.7%PRS 46.4%
-
CSI 1.0rCSI 1.9%PRS 68.0%
-
CSI 1.0rCSI 1.3%PRS 44.9%
-
CSI 1.0rCSI 3.4%PRS 43.6%
-
CSI 1.0rCSI 3.0%PRS 34.8%
-
CSI 1.0rCSI 1.9%PRS 46.7%
-
CSI 1.0rCSI 2.0%PRS 61.8%
-
CSI 1.1rCSI 1.0%PRS 33.0%
-
CSI 1.1rCSI 2.3%PRS 46.6%
-
CSI 1.1rCSI 2.5%PRS 31.7%
-
CSI 1.1rCSI 1.6%PRS 25.4%
-
CSI 1.1rCSI 1.8%PRS 36.7%
-
CSI 1.1rCSI 1.3%PRS 35.6%
-
CSI 1.1rCSI 5.7%PRS 71.5%
-
CSI 1.1rCSI 1.7%PRS 36.1%
-
CSI 1.1rCSI 4.3%PRS 28.6%
-
CSI 1.1rCSI 1.7%PRS 33.0%
-
CSI 1.1rCSI 1.6%PRS 45.7%
-
CSI 1.1rCSI 2.1%PRS 27.6%
-
CSI 1.1rCSI 1.2%PRS 37.1%
-
CSI 1.2rCSI 2.1%PRS 31.0%
-
CSI 1.2rCSI 1.8%PRS 35.4%
-
CSI 1.2rCSI 1.0%PRS 36.8%
-
CSI 1.2rCSI 1.3%PRS 47.9%
-
CSI 1.2rCSI 4.4%PRS 71.4%
-
CSI 1.2rCSI 3.6%PRS 47.5%
-
CSI 1.3rCSI 2.7%PRS 41.1%
-
CSI 1.3rCSI 1.5%PRS 20.0%
-
CSI 1.3rCSI 2.3%PRS 26.9%
-
CSI 1.3rCSI 1.3%PRS 43.7%
-
CSI 1.3rCSI 1.9%PRS 41.2%
-
CSI 1.3rCSI 1.6%PRS 28.5%
-
CSI 1.3rCSI 1.9%PRS 29.6%
-
CSI 1.3rCSI 1.5%PRS 55.2%
-
CSI 1.3rCSI 1.1%PRS 30.4%
-
CSI 1.3rCSI 1.0%PRS 42.7%
-
CSI 1.4rCSI 1.4%PRS 27.4%
-
CSI 1.4rCSI 1.7%PRS 38.7%
-
CSI 1.4rCSI 2.2%PRS 27.3%
-
CSI 1.4rCSI 1.9%PRS 35.3%
-
CSI 1.5rCSI 1.7%PRS 42.7%
-
CSI 1.5rCSI 1.5%PRS 32.4%
-
CSI 1.5rCSI 7.4%PRS 41.2%
-
CSI 1.5rCSI 2.4%PRS 40.7%
-
CSI 1.5rCSI 2.3%PRS 40.0%
-
CSI 1.5rCSI 1.7%PRS 29.8%
-
CSI 1.6rCSI 1.5%PRS 32.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3572676621
Symbol: RIP_HUMAN
Name: RPA-interacting protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16008515
Title: Identification, expression pattern, and subcellular location of human RIP isoforms.
PubMed ID: 16008515
PubMed ID: 16135809
Title: Sumoylation of the novel protein hRIPbeta is involved in replication protein A deposition in PML nuclear bodies.
PubMed ID: 16135809
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 219
- Mass: 24770
- Checksum: BAF576893B8B1B23
- Sequence:
MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN ALQSVENCPE DLAQLEELID MAVLEEIQQE LINQEQSIIS EYEKSLQFDE KCLSIMLAEW EANPLICPVC TKYNLRITSG VVVCQCGLSI PSHSSELTEQ KLRACLEGSI NEHSAHCPHT PEFSVTGGTE EKSSLLMSCL ACDTWAVIL
Genular Protein ID: 2031638004
Symbol: B3KTT3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 107
- Mass: 12398
- Checksum: A2803830616713B6
- Sequence:
MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN ALQSVENCPE DLAQLEELID MAVLEEIQQE LINQGTT