MAN1A2 | ENSG00000198162 | NCBI 10905

Details for: MAN1A2

Gene ID: 10905

Symbol: MAN1A2

Ensembl ID: ENSG00000198162

Description: mannosidase alpha class 1A member 2

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Intra-golgi and retrograde golgi-to-er traffic
(R-HSA-6811442)
Intra-golgi traffic
(R-HSA-6811438)
Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
N-glycan trimming and elongation in the cis-golgi
(R-HSA-964739)
Post-translational protein modification
(R-HSA-597592)
Progressive trimming of alpha-1,2-linked mannose residues from man9/8/7glcnac2 to produce man5glcnac2
(R-HSA-964827)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Calcium ion binding
(GO:0005509)
Carbohydrate metabolic process
(GO:0005975)
Endoplasmic reticulum
(GO:0005783)
Extracellular exosome
(GO:0070062)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Lung alveolus development
(GO:0048286)
Mannose trimming involved in glycoprotein erad pathway
(GO:1904382)
Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
(GO:0004571)
Membrane
(GO:0016020)
N-glycan processing
(GO:0006491)
Protein glycosylation
(GO:0006486)
Respiratory gaseous exchange by respiratory system
(GO:0007585)

Other Information

Proteins

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

Genular Protein ID: 3855776411

Symbol: MA1A2_HUMAN

Name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

UniProtKB Accession Codes:

O60476 Q9H510

Database IDs:

Citations:

PubMed ID: 9592125

Title: Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha-1,2-mannosidase gene involved in N-glycan maturation.

PubMed ID: 9592125

DOI: 10.1093/glycob/8.6.585

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

Length: 641
Mass: 73004
Checksum: 19DA691A9C4B0ED3
Sequence:

MTTPALLPLS GRRIPPLNLG PPSFPHHRAT LRLSEKFILL LILSAFITLC FGAFFFLPDS 
SKHKRFDLGL EDVLIPHVDA GKGAKNPGVF LIHGPDEHRH REEEERLRNK IRADHEKALE 
EAKEKLRKSR EEIRAEIQTE KNKVVQEMKI KENKPLPPVP IPNLVGIRGG DPEDNDIREK 
REKIKEMMKH AWDNYRTYGW GHNELRPIAR KGHSPNIFGS SQMGATIVDA LDTLYIMGLH 
DEFLDGQRWI EDNLDFSVNS EVSVFEVNIR FIGGLLAAYY LSGEEIFKIK AVQLAEKLLP 
AFNTPTGIPW AMVNLKSGVG RNWGWASAGS SILAEFGTLH MEFIHLSYLT GDLTYYKKVM 
HIRKLLQKMD RPNGLYPNYL NPRTGRWGQY HTSVGGLGDS FYEYLLKAWL MSDKTDHEAR 
KMYDDAIEAI EKHLIKKSRG GLTFIGEWKN GHLEKKMGHL ACFAGGMFAL GADGSRADKA 
GHYLELGAEI ARTCHESYDR TALKLGPESF KFDGAVEAVA VRQAEKYYIL RPEVIETYWY 
LWRFTHDPRY RQWGWEAALA IEKYCRVNGG FSGVKDVYSS TPTHDDVQQS FFLAETLKYL 
YLLFSGDDLL PLDHWVFNTE AHPLPVLHLA NTTLSGNPAV R

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MAN1A2

Associated with

Other Information

Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha-1,2-mannosidase gene involved in N-glycan maturation. PubMed ID: 9592125

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334